Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions
Contagious bovine pleuropneumonia (CBPP) caused by Mycoplasma mycoides subsp. mycoides (Mmm) is an economically very important cattle disease in sub-Saharan Africa. CBPP impacts animal health and poverty of livestock-dependent people through decreased animal productivity, reduced food supply, and th...
| Main Authors: | , , |
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| Format: | Journal Article |
| Language: | Inglés |
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Springer
2013
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| Online Access: | https://hdl.handle.net/10568/34422 |
| _version_ | 1855538882091679744 |
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| author | Jores, Joerg Mariner, Jeffrey C. Naessens, Jan |
| author_browse | Jores, Joerg Mariner, Jeffrey C. Naessens, Jan |
| author_facet | Jores, Joerg Mariner, Jeffrey C. Naessens, Jan |
| author_sort | Jores, Joerg |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Contagious bovine pleuropneumonia (CBPP) caused by Mycoplasma mycoides subsp. mycoides (Mmm) is an economically very important cattle disease in sub-Saharan Africa. CBPP impacts animal health and poverty of livestock-dependent people through decreased animal productivity, reduced food supply, and the cost of control measures. CBPP is a barrier to trade in many African countries and this reduces the value of livestock and the income of many value chain stakeholders. The presence of CBPP also poses a constant threat to CBPPfree countries and creates costs in terms of the measures necessary to ensure the exclusion of disease. This opinion focuses on the biomedical research needed to foster the development of better control measures for CBPP. We suggest that different vaccine development approaches are followed in parallel. Basic immunology studies and systematic OMICs studies will be necessary in order to identify the protective arms of immunity and to shed more light on the pathogenicity mechanisms in CBPP. Moreover a robust challenge model and a close collaboration with African research units will be crucial to foster and implement a new vaccine for the progressive control of this cattle plague. |
| format | Journal Article |
| id | CGSpace34422 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace344222025-11-12T04:30:48Z Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions Jores, Joerg Mariner, Jeffrey C. Naessens, Jan livestock research Contagious bovine pleuropneumonia (CBPP) caused by Mycoplasma mycoides subsp. mycoides (Mmm) is an economically very important cattle disease in sub-Saharan Africa. CBPP impacts animal health and poverty of livestock-dependent people through decreased animal productivity, reduced food supply, and the cost of control measures. CBPP is a barrier to trade in many African countries and this reduces the value of livestock and the income of many value chain stakeholders. The presence of CBPP also poses a constant threat to CBPPfree countries and creates costs in terms of the measures necessary to ensure the exclusion of disease. This opinion focuses on the biomedical research needed to foster the development of better control measures for CBPP. We suggest that different vaccine development approaches are followed in parallel. Basic immunology studies and systematic OMICs studies will be necessary in order to identify the protective arms of immunity and to shed more light on the pathogenicity mechanisms in CBPP. Moreover a robust challenge model and a close collaboration with African research units will be crucial to foster and implement a new vaccine for the progressive control of this cattle plague. 2013-12 2014-01-29T07:14:12Z 2014-01-29T07:14:12Z Journal Article https://hdl.handle.net/10568/34422 en Open Access application/pdf Springer Jores, J., Mariner, J.C. and Naessens, J. 2013. Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions. BMC Veterinary Research 44:122 |
| spellingShingle | livestock research Jores, Joerg Mariner, Jeffrey C. Naessens, Jan Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions |
| title | Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions |
| title_full | Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions |
| title_fullStr | Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions |
| title_full_unstemmed | Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions |
| title_short | Development of an improved vaccine for contagious bovine pleuropneumonia: An African perspective on challenges and proposed actions |
| title_sort | development of an improved vaccine for contagious bovine pleuropneumonia an african perspective on challenges and proposed actions |
| topic | livestock research |
| url | https://hdl.handle.net/10568/34422 |
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