A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats

Three microsatellite markers on goat chromosome 23 adjacent to the MHC were used to test for quantitative trait loci (QTL) affecting faecal worm egg count (WEC) and leukocyte traits in ten Australian Angora and twelve Australian Cashmere half-sib families (n = 16–57 per family). Data were collected...

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Autores principales: Bolormaa, S., Werf, J.H.J. van der, Walken-Brown, S.W., Marshall, Karen, Ruvinsky, A.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2010
Acceso en línea:https://hdl.handle.net/10568/339
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author Bolormaa, S.
Werf, J.H.J. van der
Walken-Brown, S.W.
Marshall, Karen
Ruvinsky, A.
author_browse Bolormaa, S.
Marshall, Karen
Ruvinsky, A.
Walken-Brown, S.W.
Werf, J.H.J. van der
author_facet Bolormaa, S.
Werf, J.H.J. van der
Walken-Brown, S.W.
Marshall, Karen
Ruvinsky, A.
author_sort Bolormaa, S.
collection Repository of Agricultural Research Outputs (CGSpace)
description Three microsatellite markers on goat chromosome 23 adjacent to the MHC were used to test for quantitative trait loci (QTL) affecting faecal worm egg count (WEC) and leukocyte traits in ten Australian Angora and twelve Australian Cashmere half-sib families (n = 16–57 per family). Data were collected from 280 Angora and 347 Cashmere kids over a 3- and 4-year period. A putative QTL affecting trichostrongyle WEC was found in two small families at the 5% chromosome-wise threshold level. The biggest QTL effect for WEC of 1.65 standard deviations (σp) was found within the region of OarCP73-BM1258. A significant QTL affecting blood eosinophil counts at the 1% chromosome–wise threshold level was detected at marker BM1258 (at 26 cM) in two Angora and Cashmere families. The magnitude of the putative QTL was 0.69 and 0.85 σp in Angora and Cashmere families, respectively. Due to the comparatively low power of the study these findings should be viewed as indicative rather than definitive.
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spelling CGSpace3392024-08-27T10:36:50Z A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats Bolormaa, S. Werf, J.H.J. van der Walken-Brown, S.W. Marshall, Karen Ruvinsky, A. Three microsatellite markers on goat chromosome 23 adjacent to the MHC were used to test for quantitative trait loci (QTL) affecting faecal worm egg count (WEC) and leukocyte traits in ten Australian Angora and twelve Australian Cashmere half-sib families (n = 16–57 per family). Data were collected from 280 Angora and 347 Cashmere kids over a 3- and 4-year period. A putative QTL affecting trichostrongyle WEC was found in two small families at the 5% chromosome-wise threshold level. The biggest QTL effect for WEC of 1.65 standard deviations (σp) was found within the region of OarCP73-BM1258. A significant QTL affecting blood eosinophil counts at the 1% chromosome–wise threshold level was detected at marker BM1258 (at 26 cM) in two Angora and Cashmere families. The magnitude of the putative QTL was 0.69 and 0.85 σp in Angora and Cashmere families, respectively. Due to the comparatively low power of the study these findings should be viewed as indicative rather than definitive. 2010-06-01 2010-01-04T14:25:07Z 2010-01-04T14:25:07Z Journal Article https://hdl.handle.net/10568/339 en Limited Access Wiley Bolormaa, S.; van der Werf, J.H.J.; Walkden-Brown, S.W.; Marshall, K.; Ruvinsky, A. 2010. A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats. Journal of Animal Breeding and Genetics. 127(3): 207 - 214
spellingShingle Bolormaa, S.
Werf, J.H.J. van der
Walken-Brown, S.W.
Marshall, Karen
Ruvinsky, A.
A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
title A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
title_full A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
title_fullStr A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
title_full_unstemmed A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
title_short A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
title_sort quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in australian goats
url https://hdl.handle.net/10568/339
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