Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya

The passive transfer of antibodies from dams to offspring via colostrum is believed to play an important role in protecting neonatal mammals from infectious disease. The study presented here investigates the uptake of colostrum by 548 calves in western Kenya maintained under smallholder farming, an...

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Main Authors: Toye, Philip G., Handel, Ian G., Gray, J., Kiara, Henry K., Thumbi, Samuel M., Jennings, A., Wyk, Ilana Conradie van, Ndila, M., Hanotte, Olivier H., Coetzer, K., Woolhouse, Mark E.J., Bronsvoort, B.M. de C.
Format: Journal Article
Language:Inglés
Published: Elsevier 2013
Subjects:
Online Access:https://hdl.handle.net/10568/33730
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author Toye, Philip G.
Handel, Ian G.
Gray, J.
Kiara, Henry K.
Thumbi, Samuel M.
Jennings, A.
Wyk, Ilana Conradie van
Ndila, M.
Hanotte, Olivier H.
Coetzer, K.
Woolhouse, Mark E.J.
Bronsvoort, B.M. de C.
author_browse Bronsvoort, B.M. de C.
Coetzer, K.
Gray, J.
Handel, Ian G.
Hanotte, Olivier H.
Jennings, A.
Kiara, Henry K.
Ndila, M.
Thumbi, Samuel M.
Toye, Philip G.
Woolhouse, Mark E.J.
Wyk, Ilana Conradie van
author_facet Toye, Philip G.
Handel, Ian G.
Gray, J.
Kiara, Henry K.
Thumbi, Samuel M.
Jennings, A.
Wyk, Ilana Conradie van
Ndila, M.
Hanotte, Olivier H.
Coetzer, K.
Woolhouse, Mark E.J.
Bronsvoort, B.M. de C.
author_sort Toye, Philip G.
collection Repository of Agricultural Research Outputs (CGSpace)
description The passive transfer of antibodies from dams to offspring via colostrum is believed to play an important role in protecting neonatal mammals from infectious disease. The study presented here investigates the uptake of colostrum by 548 calves in western Kenya maintained under smallholder farming, an important agricultural system in eastern Africa. Serum samples collected from the calves and dams at recruitment (within the first week of life) were analysed for the presence of antibodies to four tick-borne haemoparasites: Anaplasma marginale, Babesia bigemina, Theileria mutans and Theileria parva. The analysis showed that at least 89.33% of dams were seropositive for at least one of the parasites, and that 93.08% of calves for which unequivocal results were available showed evidence of having received colostrum. The maternal antibody was detected up until 21 weeks of age in the calves. Surprisingly, there was no discernible difference in mortality or growth rate between calves that had taken colostrum and those that had not. The results are also important for interpretation of serosurveys of young calves following natural infection or vaccination.
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spelling CGSpace337302024-01-17T12:58:34Z Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya Toye, Philip G. Handel, Ian G. Gray, J. Kiara, Henry K. Thumbi, Samuel M. Jennings, A. Wyk, Ilana Conradie van Ndila, M. Hanotte, Olivier H. Coetzer, K. Woolhouse, Mark E.J. Bronsvoort, B.M. de C. farming systems cattle immunology The passive transfer of antibodies from dams to offspring via colostrum is believed to play an important role in protecting neonatal mammals from infectious disease. The study presented here investigates the uptake of colostrum by 548 calves in western Kenya maintained under smallholder farming, an important agricultural system in eastern Africa. Serum samples collected from the calves and dams at recruitment (within the first week of life) were analysed for the presence of antibodies to four tick-borne haemoparasites: Anaplasma marginale, Babesia bigemina, Theileria mutans and Theileria parva. The analysis showed that at least 89.33% of dams were seropositive for at least one of the parasites, and that 93.08% of calves for which unequivocal results were available showed evidence of having received colostrum. The maternal antibody was detected up until 21 weeks of age in the calves. Surprisingly, there was no discernible difference in mortality or growth rate between calves that had taken colostrum and those that had not. The results are also important for interpretation of serosurveys of young calves following natural infection or vaccination. 2013-09 2013-10-01T06:55:45Z 2013-10-01T06:55:45Z Journal Article https://hdl.handle.net/10568/33730 en Open Access Elsevier Toye, P., Handel, I., Gray, J., Kiara, H., Thumbi, S., Jennings, A., Wyk, I.C. van, Ndila, M., Hanotte, O., Coetzer, K., Woolhouse, M. and Bronsvoort, M. 2013. Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya. Veterinary Immunology and Immunopathology 155(1-2): 129-134.
spellingShingle farming systems
cattle
immunology
Toye, Philip G.
Handel, Ian G.
Gray, J.
Kiara, Henry K.
Thumbi, Samuel M.
Jennings, A.
Wyk, Ilana Conradie van
Ndila, M.
Hanotte, Olivier H.
Coetzer, K.
Woolhouse, Mark E.J.
Bronsvoort, B.M. de C.
Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya
title Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya
title_full Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya
title_fullStr Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya
title_full_unstemmed Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya
title_short Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya
title_sort maternal antibody uptake duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western kenya
topic farming systems
cattle
immunology
url https://hdl.handle.net/10568/33730
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