H7N9 is a virus worth worrying about
Once again an animal influenza A virus has crossed the species barrier to cause an appreciable number of human cases. Now, two months after the first known human infections with the H7N9 virus, the question is: which of the paths set by previous emerging influenza viruses will it follow? One predece...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Springer
2013
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| Acceso en línea: | https://hdl.handle.net/10568/33541 |
| _version_ | 1855517298914230272 |
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| author | Horby, P. Tatem, A.J. Huang, Z. Gilbert, M. Robinson, Timothy P. Wint, G.R.W. Hayden, F.G. Van Vinh Chau, N. Shindo, N. Carson, G. Gao, Z. Hongjie, Y. Hay, S.I. Farrar, J. |
| author_browse | Carson, G. Farrar, J. Gao, Z. Gilbert, M. Hay, S.I. Hayden, F.G. Hongjie, Y. Horby, P. Huang, Z. Robinson, Timothy P. Shindo, N. Tatem, A.J. Van Vinh Chau, N. Wint, G.R.W. |
| author_facet | Horby, P. Tatem, A.J. Huang, Z. Gilbert, M. Robinson, Timothy P. Wint, G.R.W. Hayden, F.G. Van Vinh Chau, N. Shindo, N. Carson, G. Gao, Z. Hongjie, Y. Hay, S.I. Farrar, J. |
| author_sort | Horby, P. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Once again an animal influenza A virus has crossed the species barrier to cause an appreciable number of human cases. Now, two months after the first known human infections with the H7N9 virus, the question is: which of the paths set by previous emerging influenza viruses will it follow? One predecessor, H5N1, generated alarm owing to its high pathogenicity in humans. It has proved to be a tenacious adversary, remaining endemic in poultry across large parts of Asia, but thankfully it has not adapted to humans and person-to-person transmission remains rare. A second, H7N7, caused a number of mostly mild human infections in the Netherlands in 2003, with some evidence of limited person-to-person spread, but extensive poultry culling controlled it. A third, the H1N1 swine influenza virus that emerged in 2009, successfully adapted to humans and caused a pandemic. So will H7N9 prove to be controllable? Will it remain entrenched in animals? Or will it, like the H1N1 virus, stably adapt to humans and cause a pandemic? The fine line between foresight and alarmism can only be drawn in retrospect. Nevertheless, my colleagues and I consider that H7N9 has many of the traits that make a new flu virus worrisome. |
| format | Journal Article |
| id | CGSpace33541 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2013 |
| publishDateRange | 2013 |
| publishDateSort | 2013 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace335412025-11-12T04:25:38Z H7N9 is a virus worth worrying about Horby, P. Tatem, A.J. Huang, Z. Gilbert, M. Robinson, Timothy P. Wint, G.R.W. Hayden, F.G. Van Vinh Chau, N. Shindo, N. Carson, G. Gao, Z. Hongjie, Y. Hay, S.I. Farrar, J. Once again an animal influenza A virus has crossed the species barrier to cause an appreciable number of human cases. Now, two months after the first known human infections with the H7N9 virus, the question is: which of the paths set by previous emerging influenza viruses will it follow? One predecessor, H5N1, generated alarm owing to its high pathogenicity in humans. It has proved to be a tenacious adversary, remaining endemic in poultry across large parts of Asia, but thankfully it has not adapted to humans and person-to-person transmission remains rare. A second, H7N7, caused a number of mostly mild human infections in the Netherlands in 2003, with some evidence of limited person-to-person spread, but extensive poultry culling controlled it. A third, the H1N1 swine influenza virus that emerged in 2009, successfully adapted to humans and caused a pandemic. So will H7N9 prove to be controllable? Will it remain entrenched in animals? Or will it, like the H1N1 virus, stably adapt to humans and cause a pandemic? The fine line between foresight and alarmism can only be drawn in retrospect. Nevertheless, my colleagues and I consider that H7N9 has many of the traits that make a new flu virus worrisome. 2013-04 2013-08-26T14:24:00Z 2013-08-26T14:24:00Z Journal Article https://hdl.handle.net/10568/33541 en Open Access application/pdf Springer Horby, P., Tatem, A.J., Huang, Z., Gilbert, M., Robinson, T.P., Wint, G.R.W., Hayden, F.G., van Vinh Chau, N., Shindo, N., Carson, G., Gao, Z., Hongjie, Y., Hay, S.I. and Farrar, J. 2013. H7N9 is a virus worth worrying about. Nature 496(7446):399. |
| spellingShingle | Horby, P. Tatem, A.J. Huang, Z. Gilbert, M. Robinson, Timothy P. Wint, G.R.W. Hayden, F.G. Van Vinh Chau, N. Shindo, N. Carson, G. Gao, Z. Hongjie, Y. Hay, S.I. Farrar, J. H7N9 is a virus worth worrying about |
| title | H7N9 is a virus worth worrying about |
| title_full | H7N9 is a virus worth worrying about |
| title_fullStr | H7N9 is a virus worth worrying about |
| title_full_unstemmed | H7N9 is a virus worth worrying about |
| title_short | H7N9 is a virus worth worrying about |
| title_sort | h7n9 is a virus worth worrying about |
| url | https://hdl.handle.net/10568/33541 |
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