Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle

The pituitary glands of seven Boran cattle ( Bos indicus), five infected with a clone of Trypanosoma congolense IL 1180 (ILNat 3.1) transmitted by Glossina morsitans centralis and two uninfected controls, were examined by light and electron microscopy 43 (experiment 2) or 56 (experiment 1) days afte...

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Main Authors: Abebe, G., Shaw, M.K., Eley, R.M.
Format: Journal Article
Language:Inglés
Published: SAGE Publications 1993
Subjects:
Online Access:https://hdl.handle.net/10568/33258
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author Abebe, G.
Shaw, M.K.
Eley, R.M.
author_browse Abebe, G.
Eley, R.M.
Shaw, M.K.
author_facet Abebe, G.
Shaw, M.K.
Eley, R.M.
author_sort Abebe, G.
collection Repository of Agricultural Research Outputs (CGSpace)
description The pituitary glands of seven Boran cattle ( Bos indicus), five infected with a clone of Trypanosoma congolense IL 1180 (ILNat 3.1) transmitted by Glossina morsitans centralis and two uninfected controls, were examined by light and electron microscopy 43 (experiment 2) or 56 (experiment 1) days after fly challenge. The three cattle used in the first experiment included a 15-month-old female (No. 1), a 24–month-old female (No. 2), and a 21–month-old male (No. 3) as a control. In the second experiment, four cattle were used: two females (Nos. 4, 5) and one male (No. 6), all between 15 and 24 months of age, and one female control (No. 7) of similar age. In all the infected animals, dilation of both the sinusoids and microvasculature was apparent, as was an increase in the thickness of the extracellular matrix between the pituitary lobules. Trypanosomes were found in the microvasculature of the adenohypophysis and neurohypophysis in all the infected animals. Focal degenerative changes were seen in the adenohypophyseal section of glands from the infected animals euthanatized 56 days post-infection. These degenerative structural changes were confined to the somatotrophs cells. The possible role that trypanosomes in the microvasculature may play in inducing pituitary damage and dysfunction is discussed.
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spelling CGSpace332582024-05-06T08:03:44Z Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle Abebe, G. Shaw, M.K. Eley, R.M. cattle trypanosoma congolense The pituitary glands of seven Boran cattle ( Bos indicus), five infected with a clone of Trypanosoma congolense IL 1180 (ILNat 3.1) transmitted by Glossina morsitans centralis and two uninfected controls, were examined by light and electron microscopy 43 (experiment 2) or 56 (experiment 1) days after fly challenge. The three cattle used in the first experiment included a 15-month-old female (No. 1), a 24–month-old female (No. 2), and a 21–month-old male (No. 3) as a control. In the second experiment, four cattle were used: two females (Nos. 4, 5) and one male (No. 6), all between 15 and 24 months of age, and one female control (No. 7) of similar age. In all the infected animals, dilation of both the sinusoids and microvasculature was apparent, as was an increase in the thickness of the extracellular matrix between the pituitary lobules. Trypanosomes were found in the microvasculature of the adenohypophysis and neurohypophysis in all the infected animals. Focal degenerative changes were seen in the adenohypophyseal section of glands from the infected animals euthanatized 56 days post-infection. These degenerative structural changes were confined to the somatotrophs cells. The possible role that trypanosomes in the microvasculature may play in inducing pituitary damage and dysfunction is discussed. 1993-09 2013-07-03T05:26:19Z 2013-07-03T05:26:19Z Journal Article https://hdl.handle.net/10568/33258 en Limited Access SAGE Publications Abebe, G., Shaw, M. K., & Eley, R. M. (1993). Trypanosoma congolensein the Microvasculature of the Pituitary Gland of Experimentally Infected Boran Cattle (Bos indicus). Veterinary Pathology, 30(5), 401–409. https://doi.org/10.1177/030098589303000501
spellingShingle cattle
trypanosoma congolense
Abebe, G.
Shaw, M.K.
Eley, R.M.
Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle
title Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle
title_full Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle
title_fullStr Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle
title_full_unstemmed Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle
title_short Trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected Boran (Bos indicus) cattle
title_sort trypanosoma congolense in the microvasculature of the pituitary gland of experimentally infected boran bos indicus cattle
topic cattle
trypanosoma congolense
url https://hdl.handle.net/10568/33258
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AT shawmk trypanosomacongolenseinthemicrovasculatureofthepituitaryglandofexperimentallyinfectedboranbosindicuscattle
AT eleyrm trypanosomacongolenseinthemicrovasculatureofthepituitaryglandofexperimentallyinfectedboranbosindicuscattle