A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa

Pastoral cattle live in highly structured communities characterized by complex contact patterns. The present paper describes a spatially heterogeneous model for the transmission of contagious bovine pleuropneumonia (CBPP) developed specifically for pastoral communities of East Africa. The model is v...

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Main Authors: Mariner, Jeffrey C., McDermott, John J., Heesterbeek, J.A.P., Thomson, G., Roeder, P.L., Martin, S.W.
Format: Journal Article
Language:Inglés
Published: Elsevier 2006
Subjects:
Online Access:https://hdl.handle.net/10568/33125
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author Mariner, Jeffrey C.
McDermott, John J.
Heesterbeek, J.A.P.
Thomson, G.
Roeder, P.L.
Martin, S.W.
author_browse Heesterbeek, J.A.P.
Mariner, Jeffrey C.
Martin, S.W.
McDermott, John J.
Roeder, P.L.
Thomson, G.
author_facet Mariner, Jeffrey C.
McDermott, John J.
Heesterbeek, J.A.P.
Thomson, G.
Roeder, P.L.
Martin, S.W.
author_sort Mariner, Jeffrey C.
collection Repository of Agricultural Research Outputs (CGSpace)
description Pastoral cattle live in highly structured communities characterized by complex contact patterns. The present paper describes a spatially heterogeneous model for the transmission of contagious bovine pleuropneumonia (CBPP) developed specifically for pastoral communities of East Africa. The model is validated against serological data on the prevalence of CBPP infection in several communities of southern Sudan and against livestock owner information on community structure, livestock contact and cattle exchange. The model is used to assess the impact of alternative control strategies including mass and elective vaccination programmes, potential treatment regimes and the combination of vaccination and treatment in a single unified strategy. The results indicate that the eradication of CBPP using mass vaccination with currently available vaccines is unlikely to succeed. On the other hand, elective control programmes based on herd level vaccination, treatment of clinical cases or a combination of both vaccination and treatment enabled individual livestock owners to capture a large benefit in terms of reduced animal-level prevalence and mortality experience. The most promising intervention scenario was a programme which combined the vaccination of healthy animals with treatment of clinical cases.
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spelling CGSpace331252023-12-08T19:36:04Z A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa Mariner, Jeffrey C. McDermott, John J. Heesterbeek, J.A.P. Thomson, G. Roeder, P.L. Martin, S.W. contagious bovine pleuropneumonia reproduction epidemiology models policies disease transmission disease control pastoral society Pastoral cattle live in highly structured communities characterized by complex contact patterns. The present paper describes a spatially heterogeneous model for the transmission of contagious bovine pleuropneumonia (CBPP) developed specifically for pastoral communities of East Africa. The model is validated against serological data on the prevalence of CBPP infection in several communities of southern Sudan and against livestock owner information on community structure, livestock contact and cattle exchange. The model is used to assess the impact of alternative control strategies including mass and elective vaccination programmes, potential treatment regimes and the combination of vaccination and treatment in a single unified strategy. The results indicate that the eradication of CBPP using mass vaccination with currently available vaccines is unlikely to succeed. On the other hand, elective control programmes based on herd level vaccination, treatment of clinical cases or a combination of both vaccination and treatment enabled individual livestock owners to capture a large benefit in terms of reduced animal-level prevalence and mortality experience. The most promising intervention scenario was a programme which combined the vaccination of healthy animals with treatment of clinical cases. 2006-01 2013-07-03T05:26:06Z 2013-07-03T05:26:06Z Journal Article https://hdl.handle.net/10568/33125 en Limited Access Elsevier Preventive Veterinary Medicine;73(1): 75-91
spellingShingle contagious bovine pleuropneumonia
reproduction
epidemiology
models
policies
disease transmission
disease control
pastoral society
Mariner, Jeffrey C.
McDermott, John J.
Heesterbeek, J.A.P.
Thomson, G.
Roeder, P.L.
Martin, S.W.
A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa
title A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa
title_full A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa
title_fullStr A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa
title_full_unstemmed A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa
title_short A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa
title_sort heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of east africa
topic contagious bovine pleuropneumonia
reproduction
epidemiology
models
policies
disease transmission
disease control
pastoral society
url https://hdl.handle.net/10568/33125
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