Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines
A dispersed repetitive element named ingi, which is present in the genome of the protozoan parasite Trypanosoma brucei, is described. One complete 5.2-kilobase element and the ends of two others were sequenced. There were no direct or inverted terminal repeats. Rather, the ends consisted of two halv...
| Main Authors: | , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Informa UK Limited
1987
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/33070 |
| _version_ | 1855517318390480896 |
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| author | Kimmel, B.E. Ole-MoiYoi, O.K. Young, J.R. |
| author_browse | Kimmel, B.E. Ole-MoiYoi, O.K. Young, J.R. |
| author_facet | Kimmel, B.E. Ole-MoiYoi, O.K. Young, J.R. |
| author_sort | Kimmel, B.E. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | A dispersed repetitive element named ingi, which is present in the genome of the protozoan parasite Trypanosoma brucei, is described. One complete 5.2-kilobase element and the ends of two others were sequenced. There were no direct or inverted terminal repeats. Rather, the ends consisted of two halves of a previously described 512-base-pair transposable element (G. Hasan, M.J. Turner, and J.S. Cordingley, Cell 37:333-341, 1984). Oligo(dA) tails and possible insertion site duplications suggested that ingi is a retroposon. The sequenced element appears to be a pseudogene copy of an original retroposon with one or more open reading frames occupying most of its length. Significant homologies of the encoded amino acid sequences with reverse transcriptases and mammalian long interpersed nuclear element sequences suggest a remote evolutionary origin for this kind of retroposon. |
| format | Journal Article |
| id | CGSpace33070 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1987 |
| publishDateRange | 1987 |
| publishDateSort | 1987 |
| publisher | Informa UK Limited |
| publisherStr | Informa UK Limited |
| record_format | dspace |
| spelling | CGSpace330702024-08-27T10:35:03Z Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines Kimmel, B.E. Ole-MoiYoi, O.K. Young, J.R. trypanosoma brucei dispersion mammals animal diseases cell biology molecular biology A dispersed repetitive element named ingi, which is present in the genome of the protozoan parasite Trypanosoma brucei, is described. One complete 5.2-kilobase element and the ends of two others were sequenced. There were no direct or inverted terminal repeats. Rather, the ends consisted of two halves of a previously described 512-base-pair transposable element (G. Hasan, M.J. Turner, and J.S. Cordingley, Cell 37:333-341, 1984). Oligo(dA) tails and possible insertion site duplications suggested that ingi is a retroposon. The sequenced element appears to be a pseudogene copy of an original retroposon with one or more open reading frames occupying most of its length. Significant homologies of the encoded amino acid sequences with reverse transcriptases and mammalian long interpersed nuclear element sequences suggest a remote evolutionary origin for this kind of retroposon. 1987-04 2013-07-03T05:26:01Z 2013-07-03T05:26:01Z Journal Article https://hdl.handle.net/10568/33070 en Limited Access Informa UK Limited Molecular and Cellular Biology;7: l465-1475 |
| spellingShingle | trypanosoma brucei dispersion mammals animal diseases cell biology molecular biology Kimmel, B.E. Ole-MoiYoi, O.K. Young, J.R. Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| title | Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| title_full | Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| title_fullStr | Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| title_full_unstemmed | Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| title_short | Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| title_sort | ingi a 5 2 kb dispersed sequence element from trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines |
| topic | trypanosoma brucei dispersion mammals animal diseases cell biology molecular biology |
| url | https://hdl.handle.net/10568/33070 |
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