Purine-specific nucleoside N-ribohydrolase from Trypanosoma brucei brucei: Purification, specificity, and kinetic mechanism

Trypanosomes have no de novo purine biosynthesis and thus depend upon salvage pathways to obtain purines for their metabolic pathways and for the biosynthesis of nucleic acids. An inosine-adenosine-guanosine preferring nucleoside hydrolase (IAG-nucleoside hydrolase) from the African trypanosome Tryp...

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Bibliographic Details
Main Author: Parkin, D.W.
Format: Journal Article
Language:Inglés
Published: Elsevier 1996
Subjects:
Online Access:https://hdl.handle.net/10568/32992

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