An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007
An outbreak of Rift Valley fever (RVF) occurred in Kenya during November 2006 through March 2007. We characterized the magnitude of the outbreak through disease surveillance and serosurveys, and investigated contributing factors to enhance strategies for forecasting to prevent or minimize the impact...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
American Society of Tropical Medicine and Hygiene
2010
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| Acceso en línea: | https://hdl.handle.net/10568/3243 |
| _version_ | 1855520795066892288 |
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| author | Nguku, P.M. Sharif, S.K. Mutonga, D. Amwayi, S. Omolo, J.O. Mohammed, O. Farnon, E.C. Gould, L.H. Lederman, E. Rao, C. Sang, R. Schnabel, D. Feikin, D.R. Hightower, A. Njenga, M.K. Breiman, R.F. |
| author_browse | Amwayi, S. Breiman, R.F. Farnon, E.C. Feikin, D.R. Gould, L.H. Hightower, A. Lederman, E. Mohammed, O. Mutonga, D. Nguku, P.M. Njenga, M.K. Omolo, J.O. Rao, C. Sang, R. Schnabel, D. Sharif, S.K. |
| author_facet | Nguku, P.M. Sharif, S.K. Mutonga, D. Amwayi, S. Omolo, J.O. Mohammed, O. Farnon, E.C. Gould, L.H. Lederman, E. Rao, C. Sang, R. Schnabel, D. Feikin, D.R. Hightower, A. Njenga, M.K. Breiman, R.F. |
| author_sort | Nguku, P.M. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | An outbreak of Rift Valley fever (RVF) occurred in Kenya during November 2006 through March 2007. We characterized the magnitude of the outbreak through disease surveillance and serosurveys, and investigated contributing factors to enhance strategies for forecasting to prevent or minimize the impact of future outbreaks. Of 700 suspected cases, 392 met probable or confirmed case definitions; demographic data were available for 340 (87%), including 90 (26.4%) deaths. Male cases were more likely to die than females, Case Fatality Rate Ratio 1.8 (95% Confidence Interval [CI] 1.3–3.8). Serosurveys suggested an attack rate up to 13% of residents in heavily affected areas. Genetic sequencing showed high homology among viruses from this and earlier RVF outbreaks. Case areas were more likely than non-case areas to have soil types that retain surface moisture. The outbreak had a devastatingly high case-fatality rate for hospitalized patients. However, there were up to 180,000 infected mildly ill or asymptomatic people within highly affected areas. Soil type data may add specificity to climate-based forecasting models for RVF. |
| format | Journal Article |
| id | CGSpace3243 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2010 |
| publishDateRange | 2010 |
| publishDateSort | 2010 |
| publisher | American Society of Tropical Medicine and Hygiene |
| publisherStr | American Society of Tropical Medicine and Hygiene |
| record_format | dspace |
| spelling | CGSpace32432024-05-01T08:16:21Z An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 Nguku, P.M. Sharif, S.K. Mutonga, D. Amwayi, S. Omolo, J.O. Mohammed, O. Farnon, E.C. Gould, L.H. Lederman, E. Rao, C. Sang, R. Schnabel, D. Feikin, D.R. Hightower, A. Njenga, M.K. Breiman, R.F. An outbreak of Rift Valley fever (RVF) occurred in Kenya during November 2006 through March 2007. We characterized the magnitude of the outbreak through disease surveillance and serosurveys, and investigated contributing factors to enhance strategies for forecasting to prevent or minimize the impact of future outbreaks. Of 700 suspected cases, 392 met probable or confirmed case definitions; demographic data were available for 340 (87%), including 90 (26.4%) deaths. Male cases were more likely to die than females, Case Fatality Rate Ratio 1.8 (95% Confidence Interval [CI] 1.3–3.8). Serosurveys suggested an attack rate up to 13% of residents in heavily affected areas. Genetic sequencing showed high homology among viruses from this and earlier RVF outbreaks. Case areas were more likely than non-case areas to have soil types that retain surface moisture. The outbreak had a devastatingly high case-fatality rate for hospitalized patients. However, there were up to 180,000 infected mildly ill or asymptomatic people within highly affected areas. Soil type data may add specificity to climate-based forecasting models for RVF. 2010-08-05 2011-03-04T15:18:26Z 2011-03-04T15:18:26Z Journal Article https://hdl.handle.net/10568/3243 en Limited Access American Society of Tropical Medicine and Hygiene Nguku, P.M., Sharif, S.K., Mutonga, D., Amwayi, S., Omolo, J., Mohammed, O., Farnon, E.C., Gould, L.H., Lederman, E., Rao, C., Sang, R., Schnabel, D., Feikin, D.R., Hightower, A., Njenga, M.K. and Breiman, R.F. 2010. An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007. American Journal of Tropical Medicine and Hygiene 83(2 Suppl):5-13. |
| spellingShingle | Nguku, P.M. Sharif, S.K. Mutonga, D. Amwayi, S. Omolo, J.O. Mohammed, O. Farnon, E.C. Gould, L.H. Lederman, E. Rao, C. Sang, R. Schnabel, D. Feikin, D.R. Hightower, A. Njenga, M.K. Breiman, R.F. An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 |
| title | An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 |
| title_full | An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 |
| title_fullStr | An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 |
| title_full_unstemmed | An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 |
| title_short | An investigation of a major outbreak of Rift Valley Fever in Kenya: 2006-2007 |
| title_sort | investigation of a major outbreak of rift valley fever in kenya 2006 2007 |
| url | https://hdl.handle.net/10568/3243 |
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