Genetic mapping of bovine T-cell receptor complex loci
Thymic-derived lymphocytes (T cells) recognize and respond to antigens through the mediation of the T-cell receptor complex. Here we report polymorphism at each of the five loci that encode the different components of the T-cell receptor complex in cattle. These genes were mapped on the bovine genom...
| Autores principales: | , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Wiley
1997
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/30061 |
| _version_ | 1855540601421824000 |
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| author | Agaba, Morris Kemp, Stephen J. Barendse, W. Teale, A.J. |
| author_browse | Agaba, Morris Barendse, W. Kemp, Stephen J. Teale, A.J. |
| author_facet | Agaba, Morris Kemp, Stephen J. Barendse, W. Teale, A.J. |
| author_sort | Agaba, Morris |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Thymic-derived lymphocytes (T cells) recognize and respond to antigens through the mediation of the T-cell receptor complex. Here we report polymorphism at each of the five loci that encode the different components of the T-cell receptor complex in cattle. These genes were mapped on the bovine genome by genetic linkage analysis in the International Bovine Reference Panel (IBRP). These mapping data provide additional type I markers for linking the bovine genetic map with the human and mouse maps and also permit investigation of the effect of T-cell receptor polymorphism on immune responsiveness and disease susceptibility. |
| format | Journal Article |
| id | CGSpace30061 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1997 |
| publishDateRange | 1997 |
| publishDateSort | 1997 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | CGSpace300612023-12-27T20:00:53Z Genetic mapping of bovine T-cell receptor complex loci Agaba, Morris Kemp, Stephen J. Barendse, W. Teale, A.J. genetic maps lymphocytes Thymic-derived lymphocytes (T cells) recognize and respond to antigens through the mediation of the T-cell receptor complex. Here we report polymorphism at each of the five loci that encode the different components of the T-cell receptor complex in cattle. These genes were mapped on the bovine genome by genetic linkage analysis in the International Bovine Reference Panel (IBRP). These mapping data provide additional type I markers for linking the bovine genetic map with the human and mouse maps and also permit investigation of the effect of T-cell receptor polymorphism on immune responsiveness and disease susceptibility. 1997-06 2013-06-11T09:26:03Z 2013-06-11T09:26:03Z Journal Article https://hdl.handle.net/10568/30061 en Limited Access Wiley Animal Genetics;28(3): 235-237 |
| spellingShingle | genetic maps lymphocytes Agaba, Morris Kemp, Stephen J. Barendse, W. Teale, A.J. Genetic mapping of bovine T-cell receptor complex loci |
| title | Genetic mapping of bovine T-cell receptor complex loci |
| title_full | Genetic mapping of bovine T-cell receptor complex loci |
| title_fullStr | Genetic mapping of bovine T-cell receptor complex loci |
| title_full_unstemmed | Genetic mapping of bovine T-cell receptor complex loci |
| title_short | Genetic mapping of bovine T-cell receptor complex loci |
| title_sort | genetic mapping of bovine t cell receptor complex loci |
| topic | genetic maps lymphocytes |
| url | https://hdl.handle.net/10568/30061 |
| work_keys_str_mv | AT agabamorris geneticmappingofbovinetcellreceptorcomplexloci AT kempstephenj geneticmappingofbovinetcellreceptorcomplexloci AT barendsew geneticmappingofbovinetcellreceptorcomplexloci AT tealeaj geneticmappingofbovinetcellreceptorcomplexloci |