Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso
Field studies were conducted to assess the occurrence of resistance to isometamidium chloride and diminazene aceturate in trypanosomes infecting cattle in Kenedougou Province of Burkina Faso. Forty-five of the 166 villages in Kenedougou were randomly sampled and visited to assess livestock numbers,...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2003
|
| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/29969 |
| _version_ | 1855535204971577344 |
|---|---|
| author | McDermott, John J. Woitag, T. Sidibe, I. Bauer, B. Diarra, B. Ouédraogo, D. Kamuanga, M. Peregrine, A.S. Eisler, M.C. Zessin, K.H. |
| author_browse | Bauer, B. Diarra, B. Eisler, M.C. Kamuanga, M. McDermott, John J. Ouédraogo, D. Peregrine, A.S. Sidibe, I. Woitag, T. Zessin, K.H. |
| author_facet | McDermott, John J. Woitag, T. Sidibe, I. Bauer, B. Diarra, B. Ouédraogo, D. Kamuanga, M. Peregrine, A.S. Eisler, M.C. Zessin, K.H. |
| author_sort | McDermott, John J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Field studies were conducted to assess the occurrence of resistance to isometamidium chloride and diminazene aceturate in trypanosomes infecting cattle in Kenedougou Province of Burkina Faso. Forty-five of the 166 villages in Kenedougou were randomly sampled and visited to assess livestock numbers, trypanosomosis risk, and tsetse challenge. The proportion of cattle infections associated with drug-resistant trypanosomes was assessed in the nine villages with the highest trypanosome infection prevalence and one village with a confirmed history of drug-resistant infections. These studies showed that resistance to both isometamidium and diminazene was widespread. However, there was considerable variation between villages in drug-resistance parameters, with the proportion of treated cattle with trypanosome infections 3 months after isometamidium prophylaxis varying from 6.9 to 63.8% and the proportion of cattle having infections 2 weeks after treatment with diminazene varying from 0 to 36.8%. The demonstration of widespread resistance to both isometamidium and diminazene has important implications, as administration of trypanocides is the most commonly employed method to control trypanosomosis in this area. |
| format | Journal Article |
| id | CGSpace29969 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2003 |
| publishDateRange | 2003 |
| publishDateSort | 2003 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace299692024-04-25T06:01:31Z Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso McDermott, John J. Woitag, T. Sidibe, I. Bauer, B. Diarra, B. Ouédraogo, D. Kamuanga, M. Peregrine, A.S. Eisler, M.C. Zessin, K.H. cattle phytomonas drug resistance antiprotozoal agents trypanosomiasis infection Field studies were conducted to assess the occurrence of resistance to isometamidium chloride and diminazene aceturate in trypanosomes infecting cattle in Kenedougou Province of Burkina Faso. Forty-five of the 166 villages in Kenedougou were randomly sampled and visited to assess livestock numbers, trypanosomosis risk, and tsetse challenge. The proportion of cattle infections associated with drug-resistant trypanosomes was assessed in the nine villages with the highest trypanosome infection prevalence and one village with a confirmed history of drug-resistant infections. These studies showed that resistance to both isometamidium and diminazene was widespread. However, there was considerable variation between villages in drug-resistance parameters, with the proportion of treated cattle with trypanosome infections 3 months after isometamidium prophylaxis varying from 6.9 to 63.8% and the proportion of cattle having infections 2 weeks after treatment with diminazene varying from 0 to 36.8%. The demonstration of widespread resistance to both isometamidium and diminazene has important implications, as administration of trypanocides is the most commonly employed method to control trypanosomosis in this area. 2003-04 2013-06-11T09:25:38Z 2013-06-11T09:25:38Z Journal Article https://hdl.handle.net/10568/29969 en Limited Access Elsevier Acta Tropica;86(1): 93-103 |
| spellingShingle | cattle phytomonas drug resistance antiprotozoal agents trypanosomiasis infection McDermott, John J. Woitag, T. Sidibe, I. Bauer, B. Diarra, B. Ouédraogo, D. Kamuanga, M. Peregrine, A.S. Eisler, M.C. Zessin, K.H. Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso |
| title | Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso |
| title_full | Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso |
| title_fullStr | Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso |
| title_full_unstemmed | Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso |
| title_short | Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso |
| title_sort | field studies of drug resistant cattle trypanosomes in kenedougou province burkina faso |
| topic | cattle phytomonas drug resistance antiprotozoal agents trypanosomiasis infection |
| url | https://hdl.handle.net/10568/29969 |
| work_keys_str_mv | AT mcdermottjohnj fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT woitagt fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT sidibei fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT bauerb fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT diarrab fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT ouedraogod fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT kamuangam fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT peregrineas fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT eislermc fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso AT zessinkh fieldstudiesofdrugresistantcattletrypanosomesinkenedougouprovinceburkinafaso |