Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)

Random amplified polymorphic DNA (RAPD) variation is being used increasingly to characterize germplasm collections. However, the technique has limitations due to the lack of reproducibility of results under certain conditions. Here we review some of the literature on the factors that are mainly resp...

Full description

Bibliographic Details
Main Authors: Lowe, A.J., Hanotte, Olivier H., Guarino, Luigi
Format: Journal Article
Language:Inglés
Published: 1996
Subjects:
Online Access:https://hdl.handle.net/10568/29494
_version_ 1855518677310373888
author Lowe, A.J.
Hanotte, Olivier H.
Guarino, Luigi
author_browse Guarino, Luigi
Hanotte, Olivier H.
Lowe, A.J.
author_facet Lowe, A.J.
Hanotte, Olivier H.
Guarino, Luigi
author_sort Lowe, A.J.
collection Repository of Agricultural Research Outputs (CGSpace)
description Random amplified polymorphic DNA (RAPD) variation is being used increasingly to characterize germplasm collections. However, the technique has limitations due to the lack of reproducibility of results under certain conditions. Here we review some of the literature on the factors that are mainly responsible for variation in the generation of RAPD fragments, and examine ways to reduce these sources of unwanted variation. We propose a table containing a collation of all the descriptors thought necessary to describe the conditions and assessment procedures necessary for reproducible RAPD profiling of plant material. The standardization of procedure and presentation of results should facilitate the comparison of results both between and within laboratories working on similar material, and allow RAPDs to be used as a standard germplasm descriptor.
format Journal Article
id CGSpace29494
institution CGIAR Consortium
language Inglés
publishDate 1996
publishDateRange 1996
publishDateSort 1996
record_format dspace
spelling CGSpace294942022-01-29T16:04:28Z Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD) Lowe, A.J. Hanotte, Olivier H. Guarino, Luigi germplasm dna molecular genetics genetic polymorphism Random amplified polymorphic DNA (RAPD) variation is being used increasingly to characterize germplasm collections. However, the technique has limitations due to the lack of reproducibility of results under certain conditions. Here we review some of the literature on the factors that are mainly responsible for variation in the generation of RAPD fragments, and examine ways to reduce these sources of unwanted variation. We propose a table containing a collation of all the descriptors thought necessary to describe the conditions and assessment procedures necessary for reproducible RAPD profiling of plant material. The standardization of procedure and presentation of results should facilitate the comparison of results both between and within laboratories working on similar material, and allow RAPDs to be used as a standard germplasm descriptor. 1996 2013-06-11T09:23:46Z 2013-06-11T09:23:46Z Journal Article https://hdl.handle.net/10568/29494 en Limited Access Plant Genetic Resources Newsletter;no. 107: 50-54
spellingShingle germplasm
dna
molecular genetics
genetic polymorphism
Lowe, A.J.
Hanotte, Olivier H.
Guarino, Luigi
Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)
title Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)
title_full Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)
title_fullStr Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)
title_full_unstemmed Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)
title_short Standardization of molecular genetic techniques for the characterization of germplasm collections: The case of random amplified polymorphic DNA (RAPD)
title_sort standardization of molecular genetic techniques for the characterization of germplasm collections the case of random amplified polymorphic dna rapd
topic germplasm
dna
molecular genetics
genetic polymorphism
url https://hdl.handle.net/10568/29494
work_keys_str_mv AT loweaj standardizationofmoleculargenetictechniquesforthecharacterizationofgermplasmcollectionsthecaseofrandomamplifiedpolymorphicdnarapd
AT hanotteolivierh standardizationofmoleculargenetictechniquesforthecharacterizationofgermplasmcollectionsthecaseofrandomamplifiedpolymorphicdnarapd
AT guarinoluigi standardizationofmoleculargenetictechniquesforthecharacterizationofgermplasmcollectionsthecaseofrandomamplifiedpolymorphicdnarapd