Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro
Significant suppression in the incidence of cyclical development ofTrypanosonia congolense, T. vivaxandT. bruceioccurred inGlossina morsitans centralismaintained on goats immunized within vitro-propagated uncoated forms ofT. congolense, T. vivaxandT. brucei, respectively. This was observed when tset...
| Autores principales: | , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Cambridge University Press
1985
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/29458 |
| _version_ | 1855534360506138624 |
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| author | Murray, M. Hirumi, H. Moloo, S.K. |
| author_browse | Hirumi, H. Moloo, S.K. Murray, M. |
| author_facet | Murray, M. Hirumi, H. Moloo, S.K. |
| author_sort | Murray, M. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Significant suppression in the incidence of cyclical development ofTrypanosonia congolense, T. vivaxandT. bruceioccurred inGlossina morsitans centralismaintained on goats immunized within vitro-propagated uncoated forms ofT. congolense, T. vivaxandT. brucei, respectively. This was observed when tsetse given aT. congolense-infected feed were subsequently maintained on uninfected immunized goats and also when uninfected tsetse were fed on immunized goats infected withT. congolense, T. vivaxandT. brucei. Suppression of infection rates in tsetse was trypanosome species specific, but was independent of the trypanosome stock used for immunization of goats. These findings were reflected in antibody responses to uncoated trypanosomes, as measured by immunofluorescence and the solid-phase immuno radiometric binding assay. Thus, antibody from goats immunized with uncoated trypano somes of one species exhibited minimal reactivity with uncoated forms of other species of trypanosomes, but showed high levels of activity with uncoated forms of the same or unrelated stocks of the same species. However, in view of the range of hosts upon which tsetse feed, it is open to question whether the use of a vaccine which suppresses trypanosome infection rates in tsetse would have any significant effect in the field. |
| format | Journal Article |
| id | CGSpace29458 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1985 |
| publishDateRange | 1985 |
| publishDateSort | 1985 |
| publisher | Cambridge University Press |
| publisherStr | Cambridge University Press |
| record_format | dspace |
| spelling | CGSpace294582024-11-15T08:52:53Z Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro Murray, M. Hirumi, H. Moloo, S.K. trypanosoma congolense trypanosoma vivax trypanosoma brucei glossinidae goats immunization disease control animal diseases Significant suppression in the incidence of cyclical development ofTrypanosonia congolense, T. vivaxandT. bruceioccurred inGlossina morsitans centralismaintained on goats immunized within vitro-propagated uncoated forms ofT. congolense, T. vivaxandT. brucei, respectively. This was observed when tsetse given aT. congolense-infected feed were subsequently maintained on uninfected immunized goats and also when uninfected tsetse were fed on immunized goats infected withT. congolense, T. vivaxandT. brucei. Suppression of infection rates in tsetse was trypanosome species specific, but was independent of the trypanosome stock used for immunization of goats. These findings were reflected in antibody responses to uncoated trypanosomes, as measured by immunofluorescence and the solid-phase immuno radiometric binding assay. Thus, antibody from goats immunized with uncoated trypano somes of one species exhibited minimal reactivity with uncoated forms of other species of trypanosomes, but showed high levels of activity with uncoated forms of the same or unrelated stocks of the same species. However, in view of the range of hosts upon which tsetse feed, it is open to question whether the use of a vaccine which suppresses trypanosome infection rates in tsetse would have any significant effect in the field. 1985-08 2013-06-11T09:23:38Z 2013-06-11T09:23:38Z Journal Article https://hdl.handle.net/10568/29458 en Limited Access Cambridge University Press Parasitology;91: 53-66 |
| spellingShingle | trypanosoma congolense trypanosoma vivax trypanosoma brucei glossinidae goats immunization disease control animal diseases Murray, M. Hirumi, H. Moloo, S.K. Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| title | Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| title_full | Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| title_fullStr | Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| title_full_unstemmed | Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| title_short | Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| title_sort | suppression of trypanosoma congolense trypanosoma vivax and trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro |
| topic | trypanosoma congolense trypanosoma vivax trypanosoma brucei glossinidae goats immunization disease control animal diseases |
| url | https://hdl.handle.net/10568/29458 |
| work_keys_str_mv | AT murraym suppressionoftrypanosomacongolensetrypanosomavivaxandtrypanosomabruceiinfectionratesintsetsefliesmaintainedongoatsimmunisedwithuncoatedformsoftrypanosomesgrowninvitro AT hirumih suppressionoftrypanosomacongolensetrypanosomavivaxandtrypanosomabruceiinfectionratesintsetsefliesmaintainedongoatsimmunisedwithuncoatedformsoftrypanosomesgrowninvitro AT moloosk suppressionoftrypanosomacongolensetrypanosomavivaxandtrypanosomabruceiinfectionratesintsetsefliesmaintainedongoatsimmunisedwithuncoatedformsoftrypanosomesgrowninvitro |