Antigenic variation in Trypanosoma vivax. Isolation of a serodeme
Studies of antigenic variation inTrypanosoma vivaxhave been hindered by its low infectivity to laboratory hosts and difficulties in obtaining defined cloned populations. The recent isolation of mouse-infectiveT. vivaxhas partially overcome the first problem. We have developed a highly efficient clon...
| Main Authors: | , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Cambridge University Press
1984
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/29431 |
| _version_ | 1855535871459065856 |
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| author | Barry, J.D. Gathuo, H. |
| author_browse | Barry, J.D. Gathuo, H. |
| author_facet | Barry, J.D. Gathuo, H. |
| author_sort | Barry, J.D. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Studies of antigenic variation inTrypanosoma vivaxhave been hindered by its low infectivity to laboratory hosts and difficulties in obtaining defined cloned populations. The recent isolation of mouse-infectiveT. vivaxhas partially overcome the first problem. We have developed a highly efficient cloning technique which has been applied to the isolation of a collection of 71 clones, representing 31 distinct variable antigen types, of mouse-infectiveT. vivaxfrom Nigeria. This serodeme showed no cross-reaction with severalT. brucei-group serodemes, but some cross-reaction with naturally occurring KenyanT. vivax. |
| format | Journal Article |
| id | CGSpace29431 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1984 |
| publishDateRange | 1984 |
| publishDateSort | 1984 |
| publisher | Cambridge University Press |
| publisherStr | Cambridge University Press |
| record_format | dspace |
| spelling | CGSpace294312024-11-15T08:52:55Z Antigenic variation in Trypanosoma vivax. Isolation of a serodeme Barry, J.D. Gathuo, H. trypanosoma vivax antigens variants animal diseases Studies of antigenic variation inTrypanosoma vivaxhave been hindered by its low infectivity to laboratory hosts and difficulties in obtaining defined cloned populations. The recent isolation of mouse-infectiveT. vivaxhas partially overcome the first problem. We have developed a highly efficient cloning technique which has been applied to the isolation of a collection of 71 clones, representing 31 distinct variable antigen types, of mouse-infectiveT. vivaxfrom Nigeria. This serodeme showed no cross-reaction with severalT. brucei-group serodemes, but some cross-reaction with naturally occurring KenyanT. vivax. 1984-08 2013-06-11T09:23:32Z 2013-06-11T09:23:32Z Journal Article https://hdl.handle.net/10568/29431 en Limited Access Cambridge University Press Parasitology;89: 49-58 |
| spellingShingle | trypanosoma vivax antigens variants animal diseases Barry, J.D. Gathuo, H. Antigenic variation in Trypanosoma vivax. Isolation of a serodeme |
| title | Antigenic variation in Trypanosoma vivax. Isolation of a serodeme |
| title_full | Antigenic variation in Trypanosoma vivax. Isolation of a serodeme |
| title_fullStr | Antigenic variation in Trypanosoma vivax. Isolation of a serodeme |
| title_full_unstemmed | Antigenic variation in Trypanosoma vivax. Isolation of a serodeme |
| title_short | Antigenic variation in Trypanosoma vivax. Isolation of a serodeme |
| title_sort | antigenic variation in trypanosoma vivax isolation of a serodeme |
| topic | trypanosoma vivax antigens variants animal diseases |
| url | https://hdl.handle.net/10568/29431 |
| work_keys_str_mv | AT barryjd antigenicvariationintrypanosomavivaxisolationofaserodeme AT gathuoh antigenicvariationintrypanosomavivaxisolationofaserodeme |