Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense
Genetic proximity between two karyotypic groups of Trypanosoma congolense was investigated using as hybridization probes: (i) total genomic DNA, (ii) a 35 nucleotide long synthetic oligonucleotide, and (iii) non-variant antigen type (non-VAT) specific complementary DNAs. The phylogenetic relationshi...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Cambridge University Press
1986
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/29415 |
| _version_ | 1855538390293807104 |
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| author | Majiwa, Phelix A.O. Hamers, R. Meirvenne, N. van Matthyssens, G. |
| author_browse | Hamers, R. Majiwa, Phelix A.O. Matthyssens, G. Meirvenne, N. van |
| author_facet | Majiwa, Phelix A.O. Hamers, R. Meirvenne, N. van Matthyssens, G. |
| author_sort | Majiwa, Phelix A.O. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Genetic proximity between two karyotypic groups of Trypanosoma congolense was investigated using as hybridization probes: (i) total genomic DNA, (ii) a 35 nucleotide long synthetic oligonucleotide, and (iii) non-variant antigen type (non-VAT) specific complementary DNAs. The phylogenetic relationship between Trypanosoma brucei and T. evansi, both of which are accepted species in the subgenus Trypanozoon, was used as a reference to assess the phylogenetic proximity of the two groups of T. congolense. Results indicate that some morphologically indistinguishable T. congolense populations differ in a variety of molecular and genetic properties: molecular karyotypes, majority of the DNA sequences, and the restriction enzyme sites in the genomic environments of various conserved genes. The implications of these findings for trypanosome evolution and T. congolense epidemiology are discussed. |
| format | Journal Article |
| id | CGSpace29415 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1986 |
| publishDateRange | 1986 |
| publishDateSort | 1986 |
| publisher | Cambridge University Press |
| publisherStr | Cambridge University Press |
| record_format | dspace |
| spelling | CGSpace294152024-11-15T08:53:01Z Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense Majiwa, Phelix A.O. Hamers, R. Meirvenne, N. van Matthyssens, G. trypanosoma congolense genetics animal diseases Genetic proximity between two karyotypic groups of Trypanosoma congolense was investigated using as hybridization probes: (i) total genomic DNA, (ii) a 35 nucleotide long synthetic oligonucleotide, and (iii) non-variant antigen type (non-VAT) specific complementary DNAs. The phylogenetic relationship between Trypanosoma brucei and T. evansi, both of which are accepted species in the subgenus Trypanozoon, was used as a reference to assess the phylogenetic proximity of the two groups of T. congolense. Results indicate that some morphologically indistinguishable T. congolense populations differ in a variety of molecular and genetic properties: molecular karyotypes, majority of the DNA sequences, and the restriction enzyme sites in the genomic environments of various conserved genes. The implications of these findings for trypanosome evolution and T. congolense epidemiology are discussed. 1986-10 2013-06-11T09:23:29Z 2013-06-11T09:23:29Z Journal Article https://hdl.handle.net/10568/29415 en Limited Access Cambridge University Press Parasitology;93: 291-304 |
| spellingShingle | trypanosoma congolense genetics animal diseases Majiwa, Phelix A.O. Hamers, R. Meirvenne, N. van Matthyssens, G. Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense |
| title | Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense |
| title_full | Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense |
| title_fullStr | Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense |
| title_full_unstemmed | Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense |
| title_short | Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense |
| title_sort | evidence for genetic diversity in trypanosoma nannomonas congolense |
| topic | trypanosoma congolense genetics animal diseases |
| url | https://hdl.handle.net/10568/29415 |
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