Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus
The initiation of feeding of infected Rhipicephalus appendiculatus adults induces the rapid development of Theileria parva sporoblasts within the salivary gland acini leading to the production of numerous sporozoites which are inoculated into the mammalian host initiating infection. In this study th...
| Main Authors: | , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Cambridge University Press
1995
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/29384 |
| _version_ | 1855534894038384640 |
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| author | Shaw, M.K. Young, A.S. |
| author_browse | Shaw, M.K. Young, A.S. |
| author_facet | Shaw, M.K. Young, A.S. |
| author_sort | Shaw, M.K. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The initiation of feeding of infected Rhipicephalus appendiculatus adults induces the rapid development of Theileria parva sporoblasts within the salivary gland acini leading to the production of numerous sporozoites which are inoculated into the mammalian host initiating infection. In this study the pattern of development, host cell specificity and emission of T. parva sporozoites within the salivary glands of heavily infected, 4-day fed adult R. appendiculatus ticks was examined. Infected acini were randomly distributed throughout the salivary gland. Sporozoite development within each gland was not synchronized and wide variation in the rate of parasite development, which correlated with the secretory activity of the individual acinus, was observed in all glands examined. Previous studies had shown that T. parva developed primarily in Type III `e' cells. However, in heavily infected salivary glands sporogony and the emission of mature sporozoites also occurred in `c' cells of Type II acini. Sporozoite emission from infected cells occurred by a process similar to apocrine secretion. The loss of the apical membrane of the infected cell allowed sporozoites free access to the lumen of the acinus and into the collecting ducts of the salivary gland. Sporozoite discharge was gradual since few parasites were found in the acinus valve or in the collecting ducts. Furthermore, the small size of the acinar valve aperature ensures that only small numbers of sporozoites can be released at any one time from an infected acinus. |
| format | Journal Article |
| id | CGSpace29384 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1995 |
| publishDateRange | 1995 |
| publishDateSort | 1995 |
| publisher | Cambridge University Press |
| publisherStr | Cambridge University Press |
| record_format | dspace |
| spelling | CGSpace293842024-11-15T08:52:55Z Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus Shaw, M.K. Young, A.S. theileria parva rhipicephalus appendiculatus salivary glands cattle The initiation of feeding of infected Rhipicephalus appendiculatus adults induces the rapid development of Theileria parva sporoblasts within the salivary gland acini leading to the production of numerous sporozoites which are inoculated into the mammalian host initiating infection. In this study the pattern of development, host cell specificity and emission of T. parva sporozoites within the salivary glands of heavily infected, 4-day fed adult R. appendiculatus ticks was examined. Infected acini were randomly distributed throughout the salivary gland. Sporozoite development within each gland was not synchronized and wide variation in the rate of parasite development, which correlated with the secretory activity of the individual acinus, was observed in all glands examined. Previous studies had shown that T. parva developed primarily in Type III `e' cells. However, in heavily infected salivary glands sporogony and the emission of mature sporozoites also occurred in `c' cells of Type II acini. Sporozoite emission from infected cells occurred by a process similar to apocrine secretion. The loss of the apical membrane of the infected cell allowed sporozoites free access to the lumen of the acinus and into the collecting ducts of the salivary gland. Sporozoite discharge was gradual since few parasites were found in the acinus valve or in the collecting ducts. Furthermore, the small size of the acinar valve aperature ensures that only small numbers of sporozoites can be released at any one time from an infected acinus. 1995-08 2013-06-11T09:23:23Z 2013-06-11T09:23:23Z Journal Article https://hdl.handle.net/10568/29384 en Limited Access Cambridge University Press Parasitology;111: 153-160 |
| spellingShingle | theileria parva rhipicephalus appendiculatus salivary glands cattle Shaw, M.K. Young, A.S. Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus |
| title | Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus |
| title_full | Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus |
| title_fullStr | Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus |
| title_full_unstemmed | Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus |
| title_short | Differential development and emission of Theileria parva sporozoites from the salivary gland of Rhipicephalus appendiculatus |
| title_sort | differential development and emission of theileria parva sporozoites from the salivary gland of rhipicephalus appendiculatus |
| topic | theileria parva rhipicephalus appendiculatus salivary glands cattle |
| url | https://hdl.handle.net/10568/29384 |
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