Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva
Summary This study examines several aspects of a polymorphic, immunodominant molecule (P!M) found in the protozoan parasite. Theileria parva. The antigen is present in all T. p. parva stocks examined, and in the related subspecies, T. p. bovis and T. p. lawrencei. It is the predominant antigen recog...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Wiley
1991
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/29374 |
| _version_ | 1855513060111810560 |
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| author | Toye, Philip G. Goddeeris, M. Iams, K.P. Musoke, A.J. Morrison, W. Ivan |
| author_browse | Goddeeris, M. Iams, K.P. Morrison, W. Ivan Musoke, A.J. Toye, Philip G. |
| author_facet | Toye, Philip G. Goddeeris, M. Iams, K.P. Musoke, A.J. Morrison, W. Ivan |
| author_sort | Toye, Philip G. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Summary This study examines several aspects of a polymorphic, immunodominant molecule (P!M) found in the protozoan parasite. Theileria parva. The antigen is present in all T. p. parva stocks examined, and in the related subspecies, T. p. bovis and T. p. lawrencei. It is the predominant antigen recognized by antisera from immune cattle on Western blot analysis of schizont‐infected lymphocytes, and is the only antigen which has been shown to react with anti‐schizont monoclonal antibodies (MoAbs) on Western blots or in immunoprecipitations. The antigen shows polymorphism in both size and expression of antibody epitopes among the different stocks of T. parva. The antigen is present in sporozoites as well as schizonts. |
| format | Journal Article |
| id | CGSpace29374 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1991 |
| publishDateRange | 1991 |
| publishDateSort | 1991 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | CGSpace293742024-05-01T08:15:12Z Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva Toye, Philip G. Goddeeris, M. Iams, K.P. Musoke, A.J. Morrison, W. Ivan cattle theileria parva animal diseases immunity disease control sporozoites immunology parasitology Summary This study examines several aspects of a polymorphic, immunodominant molecule (P!M) found in the protozoan parasite. Theileria parva. The antigen is present in all T. p. parva stocks examined, and in the related subspecies, T. p. bovis and T. p. lawrencei. It is the predominant antigen recognized by antisera from immune cattle on Western blot analysis of schizont‐infected lymphocytes, and is the only antigen which has been shown to react with anti‐schizont monoclonal antibodies (MoAbs) on Western blots or in immunoprecipitations. The antigen shows polymorphism in both size and expression of antibody epitopes among the different stocks of T. parva. The antigen is present in sporozoites as well as schizonts. 1991-01 2013-06-11T09:23:21Z 2013-06-11T09:23:21Z Journal Article https://hdl.handle.net/10568/29374 en Limited Access Wiley Parasite Immunology;13: 49-62 |
| spellingShingle | cattle theileria parva animal diseases immunity disease control sporozoites immunology parasitology Toye, Philip G. Goddeeris, M. Iams, K.P. Musoke, A.J. Morrison, W. Ivan Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva |
| title | Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva |
| title_full | Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva |
| title_fullStr | Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva |
| title_full_unstemmed | Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva |
| title_short | Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva |
| title_sort | characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of theileria parva |
| topic | cattle theileria parva animal diseases immunity disease control sporozoites immunology parasitology |
| url | https://hdl.handle.net/10568/29374 |
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