Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks

Summary Monoclonal antibodies were raised against sporozoites of Theileria parva. One of these antibodies (MAbDi) neutralized the infectivity of sporozoites for lymphocytes in vitro and for cattle in vivo. Neutralization seemed to occur by blocking sporozoite entry into the cell. MAbDi neutralized s...

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Autores principales: Dobbelaere, D.A.E., Spooner, P.R., Barry, W.C., Irvin, A.D.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 1984
Materias:
Acceso en línea:https://hdl.handle.net/10568/29343
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author Dobbelaere, D.A.E.
Spooner, P.R.
Barry, W.C.
Irvin, A.D.
author_browse Barry, W.C.
Dobbelaere, D.A.E.
Irvin, A.D.
Spooner, P.R.
author_facet Dobbelaere, D.A.E.
Spooner, P.R.
Barry, W.C.
Irvin, A.D.
author_sort Dobbelaere, D.A.E.
collection Repository of Agricultural Research Outputs (CGSpace)
description Summary Monoclonal antibodies were raised against sporozoites of Theileria parva. One of these antibodies (MAbDi) neutralized the infectivity of sporozoites for lymphocytes in vitro and for cattle in vivo. Neutralization seemed to occur by blocking sporozoite entry into the cell. MAbDi neutralized sporozoites of four unrelated stocks of T. parva, indicating the presence of a common antigenic determinant which may be important in initiating protective immunity.
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spelling CGSpace293432024-05-01T08:20:09Z Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks Dobbelaere, D.A.E. Spooner, P.R. Barry, W.C. Irvin, A.D. theileria parva monoclonal antibodies Summary Monoclonal antibodies were raised against sporozoites of Theileria parva. One of these antibodies (MAbDi) neutralized the infectivity of sporozoites for lymphocytes in vitro and for cattle in vivo. Neutralization seemed to occur by blocking sporozoite entry into the cell. MAbDi neutralized sporozoites of four unrelated stocks of T. parva, indicating the presence of a common antigenic determinant which may be important in initiating protective immunity. 1984-07 2013-06-11T09:23:15Z 2013-06-11T09:23:15Z Journal Article https://hdl.handle.net/10568/29343 en Limited Access Wiley Parasite Immunology;6: 361-370
spellingShingle theileria parva
monoclonal antibodies
Dobbelaere, D.A.E.
Spooner, P.R.
Barry, W.C.
Irvin, A.D.
Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks
title Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks
title_full Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks
title_fullStr Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks
title_full_unstemmed Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks
title_short Monoclonal antibody neutralizes the sporozoite stage of different Theileria parva stocks
title_sort monoclonal antibody neutralizes the sporozoite stage of different theileria parva stocks
topic theileria parva
monoclonal antibodies
url https://hdl.handle.net/10568/29343
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AT spoonerpr monoclonalantibodyneutralizesthesporozoitestageofdifferenttheileriaparvastocks
AT barrywc monoclonalantibodyneutralizesthesporozoitestageofdifferenttheileriaparvastocks
AT irvinad monoclonalantibodyneutralizesthesporozoitestageofdifferenttheileriaparvastocks