Endemic stability - a veterinary idea applied to human public health

Endemic stability is an epidemiological state of a population, in which clinical disease is scarce despite high level of infection. The notion was developed to describe patterns of tick-borne disease in cattle. However, we propose a general, nodes of endemic stability that is applicable to a broader...

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Detalles Bibliográficos
Autores principales: Coleman, P.G., Perry, Brian D., Woolhouse, Mark E.J.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2001
Materias:
Acceso en línea:https://hdl.handle.net/10568/29165
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author Coleman, P.G.
Perry, Brian D.
Woolhouse, Mark E.J.
author_browse Coleman, P.G.
Perry, Brian D.
Woolhouse, Mark E.J.
author_facet Coleman, P.G.
Perry, Brian D.
Woolhouse, Mark E.J.
author_sort Coleman, P.G.
collection Repository of Agricultural Research Outputs (CGSpace)
description Endemic stability is an epidemiological state of a population, in which clinical disease is scarce despite high level of infection. The notion was developed to describe patterns of tick-borne disease in cattle. However, we propose a general, nodes of endemic stability that is applicable to a broader range of diseases that are important in public health, including malaria, rubella, and mumps. We postulate that endemic stability requires only that (1) the probability, or severity, of clinical disease after infection increases with age, and (2) after one infection, the probability that subsequent infections result in disease is reduced. We present these criteria in simple mathematical terms. Our hypothesis predicts that partial disease control activities might, under certain circumstances, lead to an increase in disease incidence. We discuss the implications, for public health interventions.
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spelling CGSpace291652024-04-25T06:00:23Z Endemic stability - a veterinary idea applied to human public health Coleman, P.G. Perry, Brian D. Woolhouse, Mark E.J. endemics animal diseases public health Endemic stability is an epidemiological state of a population, in which clinical disease is scarce despite high level of infection. The notion was developed to describe patterns of tick-borne disease in cattle. However, we propose a general, nodes of endemic stability that is applicable to a broader range of diseases that are important in public health, including malaria, rubella, and mumps. We postulate that endemic stability requires only that (1) the probability, or severity, of clinical disease after infection increases with age, and (2) after one infection, the probability that subsequent infections result in disease is reduced. We present these criteria in simple mathematical terms. Our hypothesis predicts that partial disease control activities might, under certain circumstances, lead to an increase in disease incidence. We discuss the implications, for public health interventions. 2001-04 2013-06-11T09:22:38Z 2013-06-11T09:22:38Z Journal Article https://hdl.handle.net/10568/29165 en Limited Access Elsevier Lancet;357(9264): 1284-1286
spellingShingle endemics
animal diseases
public health
Coleman, P.G.
Perry, Brian D.
Woolhouse, Mark E.J.
Endemic stability - a veterinary idea applied to human public health
title Endemic stability - a veterinary idea applied to human public health
title_full Endemic stability - a veterinary idea applied to human public health
title_fullStr Endemic stability - a veterinary idea applied to human public health
title_full_unstemmed Endemic stability - a veterinary idea applied to human public health
title_short Endemic stability - a veterinary idea applied to human public health
title_sort endemic stability a veterinary idea applied to human public health
topic endemics
animal diseases
public health
url https://hdl.handle.net/10568/29165
work_keys_str_mv AT colemanpg endemicstabilityaveterinaryideaappliedtohumanpublichealth
AT perrybriand endemicstabilityaveterinaryideaappliedtohumanpublichealth
AT woolhousemarkej endemicstabilityaveterinaryideaappliedtohumanpublichealth