Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax
The purine salvage pathway of parasitic protozoa is currently considered as a target for drug development because these organisms cannot synthesize purines de novo. Insight into the structure and mechanism of the involved enzymes can aid in the development of potent inhibitors, leading to new curati...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Elsevier
2001
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/28931 |
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