Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep

Myrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock. The anthelmintic effects/activities of leaves and fruits of M. africana and fruits of R. melan...

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Autores principales: Githiori, J.B., Höglund, J., Waller, P.J., Baker, R.L.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2002
Materias:
Acceso en línea:https://hdl.handle.net/10568/28895
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author Githiori, J.B.
Höglund, J.
Waller, P.J.
Baker, R.L.
author_browse Baker, R.L.
Githiori, J.B.
Höglund, J.
Waller, P.J.
author_facet Githiori, J.B.
Höglund, J.
Waller, P.J.
Baker, R.L.
author_sort Githiori, J.B.
collection Repository of Agricultural Research Outputs (CGSpace)
description Myrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock. The anthelmintic effects/activities of leaves and fruits of M. africana and fruits of R. melanophloeos were tested in sheep experimentally infected with the nematode parasite Haemonchus contortus. Male lambs were infected with 3000–5000 third stage larvae of H. contortus and treated 28 days after inoculation with concoctions made from leaves or fruits of the plants. No significant reduction in faecal nematode egg counts was observed with any of the concoctions at any of the doses tested. Packed red cell volume decreased and live weight increased at similar rates in treated and control groups, thus there was no significant effect of treatment. The results showed that the tested extracts of the M. africana and R. melanophloeos were not efficacious against H. contortus in sheep.
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spelling CGSpace288952024-05-01T08:16:11Z Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep Githiori, J.B. Höglund, J. Waller, P.J. Baker, R.L. drug plants haemonchus contortus sheep nematoda anthelmintics traditional medicines myrsinaceae pharmacology Myrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock. The anthelmintic effects/activities of leaves and fruits of M. africana and fruits of R. melanophloeos were tested in sheep experimentally infected with the nematode parasite Haemonchus contortus. Male lambs were infected with 3000–5000 third stage larvae of H. contortus and treated 28 days after inoculation with concoctions made from leaves or fruits of the plants. No significant reduction in faecal nematode egg counts was observed with any of the concoctions at any of the doses tested. Packed red cell volume decreased and live weight increased at similar rates in treated and control groups, thus there was no significant effect of treatment. The results showed that the tested extracts of the M. africana and R. melanophloeos were not efficacious against H. contortus in sheep. 2002-05 2013-05-06T07:01:41Z 2013-05-06T07:01:41Z Journal Article https://hdl.handle.net/10568/28895 en Limited Access Elsevier Journal of Ethnopharmacology;80(2-3): 187-191
spellingShingle drug plants
haemonchus contortus
sheep
nematoda
anthelmintics
traditional medicines
myrsinaceae
pharmacology
Githiori, J.B.
Höglund, J.
Waller, P.J.
Baker, R.L.
Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
title Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
title_full Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
title_fullStr Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
title_full_unstemmed Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
title_short Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
title_sort anthelmintic activity of preparations derived from myrsine africana and rapanea melanophloeos against the nematode parasite haemonchus contortus of sheep
topic drug plants
haemonchus contortus
sheep
nematoda
anthelmintics
traditional medicines
myrsinaceae
pharmacology
url https://hdl.handle.net/10568/28895
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