In vitro simulation of immuno-suppression caused by Trypanosoma brucei: Active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression

Experimental infections of mice with the African trypanosome Trypanosoma brucei lead to a profound state of T-cell unresponsiveness in the lymph node cell (LNC) compartment. This suppression is mediated by macrophage-like cells which inhibit interleukin 2 (IL-2) secretion and down-regulate IL-2 rece...

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Bibliographic Details
Main Authors: Darji, A., Beschin, A., Sileghem, M.R., Heremans, H., Brys, L., Baetselier, P. de
Format: Journal Article
Language:Inglés
Published: 1996
Subjects:
Online Access:https://hdl.handle.net/10568/28753

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