Cover Image
QR Code

Polymorphisms in the TNFa but not in TNFb microsatellite and correlation with trypanosomiasis in mice

The tumor necrosis factor (TNF) locus comprises the tandemly arranged genes coding for Tnfa (cachectin)and Tnfb (lymphotoxin-alpha) (Semon et al. 1987). In mice, the TNF locus is located on chromosome 17 (MMU17) in the major histocompatibility complex (MHC)region. Tnfa and soluble lymphotoxin alpha...

Full description

Main Authors: Iraqi, F.A., Teale, A.J.
Format: Journal Article
Language:Inglés
Published: 1998
Subjects:
microsatellites
genetic markers
polymorphism
cytokines
mice
Online Access:https://hdl.handle.net/10568/28701
Summary:The tumor necrosis factor (TNF) locus comprises the tandemly arranged genes coding for Tnfa (cachectin)and Tnfb (lymphotoxin-alpha) (Semon et al. 1987). In mice, the TNF locus is located on chromosome 17 (MMU17) in the major histocompatibility complex (MHC)region. Tnfa and soluble lymphotoxin alpha are cytokines with similar biological activities.

Similar Items