Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis
An experiment was carried out to evaluate anthelmintic activities of three herbal plants, namely; Dodonea viscose, Albizzia gummifera and Veronia amygdalina against gastrointestinal nematode infections in sheeThe experiment was set in a parallel group design (PGD) with five treatment groups each con...
| Autores principales: | , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
2004
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| Acceso en línea: | https://hdl.handle.net/10568/28523 |
| _version_ | 1855526113766277120 |
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| author | Biftu, D. Nurfeta, A. Jobre, Y. |
| author_browse | Biftu, D. Jobre, Y. Nurfeta, A. |
| author_facet | Biftu, D. Nurfeta, A. Jobre, Y. |
| author_sort | Biftu, D. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | An experiment was carried out to evaluate anthelmintic activities of three herbal plants, namely; Dodonea viscose, Albizzia gummifera and Veronia amygdalina against gastrointestinal nematode infections in sheeThe experiment was set in a parallel group design (PGD) with five treatment groups each consisting four animals. The first group (G1) was treated with Albendazole (negative control) and the remaining three groups (G2, G3, and G4) received crude extracts of the candidate herbs. The fifth group (G5) was left untreated (positive control). Efficacy of the tested materials was measured based on the significances in the reduction in mean faecal egg count (MFECC) and improvements in mean body weight changes (MBWC) before and after treatments. Albizzia gummifera showed significant (p<O.C05) anthelmintic activities with MFECC (%) of52.2±0.71, and, MBWC (%) of 21.0±1.1. Conversely, no significant (p>0.05) anthelementic activities were observed with Dodonea viscose (MFECC (%)=1.2±0.56, and MBWC =10.2±1.96,P>0.05) and Veronia amygdalina (MFECC (%)=-5.7±0.5 and MBWC (%)4.2±10. Albizzia gummifera was thus proved to bring maximum anthelmintic effects. However, further experiments need to be carried out to determine the optimal curative dose without any untoward toxicity effect on recipient subjects. In addition, it is recommended to evaluate the medicinal effects of the roots and barks of Albizzia gummifera against various species of helminths. This study also revealed that not all herbal plants traditionally used by farmers have anthelmintic effects. Future evaluation of medicinal values of indigenous herbs in Ethiopia is needed and conducted following standard procedures employing both in vitro and in vivo experiments. |
| format | Journal Article |
| id | CGSpace28523 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2004 |
| publishDateRange | 2004 |
| publishDateSort | 2004 |
| record_format | dspace |
| spelling | CGSpace285232022-01-29T16:15:52Z Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis Biftu, D. Nurfeta, A. Jobre, Y. anthelmintics crude fibre leaves extracts indigenous organisms gastrointestinal agents nematoda sheep (caprinae) drug plants plant collections processing body weight faeces herbaceous plants An experiment was carried out to evaluate anthelmintic activities of three herbal plants, namely; Dodonea viscose, Albizzia gummifera and Veronia amygdalina against gastrointestinal nematode infections in sheeThe experiment was set in a parallel group design (PGD) with five treatment groups each consisting four animals. The first group (G1) was treated with Albendazole (negative control) and the remaining three groups (G2, G3, and G4) received crude extracts of the candidate herbs. The fifth group (G5) was left untreated (positive control). Efficacy of the tested materials was measured based on the significances in the reduction in mean faecal egg count (MFECC) and improvements in mean body weight changes (MBWC) before and after treatments. Albizzia gummifera showed significant (p<O.C05) anthelmintic activities with MFECC (%) of52.2±0.71, and, MBWC (%) of 21.0±1.1. Conversely, no significant (p>0.05) anthelementic activities were observed with Dodonea viscose (MFECC (%)=1.2±0.56, and MBWC =10.2±1.96,P>0.05) and Veronia amygdalina (MFECC (%)=-5.7±0.5 and MBWC (%)4.2±10. Albizzia gummifera was thus proved to bring maximum anthelmintic effects. However, further experiments need to be carried out to determine the optimal curative dose without any untoward toxicity effect on recipient subjects. In addition, it is recommended to evaluate the medicinal effects of the roots and barks of Albizzia gummifera against various species of helminths. This study also revealed that not all herbal plants traditionally used by farmers have anthelmintic effects. Future evaluation of medicinal values of indigenous herbs in Ethiopia is needed and conducted following standard procedures employing both in vitro and in vivo experiments. 2004 2013-05-06T07:00:47Z 2013-05-06T07:00:47Z Journal Article https://hdl.handle.net/10568/28523 en Limited Access Ethiopian Veterinary Journal;8(2): 57-65 |
| spellingShingle | anthelmintics crude fibre leaves extracts indigenous organisms gastrointestinal agents nematoda sheep (caprinae) drug plants plant collections processing body weight faeces herbaceous plants Biftu, D. Nurfeta, A. Jobre, Y. Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| title | Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| title_full | Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| title_fullStr | Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| title_full_unstemmed | Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| title_short | Evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| title_sort | evaluation of anthelmintic activities of crude leaf extracts of three indigenous herbal plants against ovine gastrointestinal nematodosis |
| topic | anthelmintics crude fibre leaves extracts indigenous organisms gastrointestinal agents nematoda sheep (caprinae) drug plants plant collections processing body weight faeces herbaceous plants |
| url | https://hdl.handle.net/10568/28523 |
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