Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe

Analysis of the transmission dynamics of Cowdria ruminantium, the tick-borne rickettsial agent of heartwater in ruminants, requires accurate measures of infection in vector populations. To obtain these, Amblyomma hebraeum ticks were collected at two heartwater-endemic locations in the lowveld and hi...

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Autores principales: Peter, T.F., Perry, Brian D., O'Callaghan, C.J., Medley, G.F., Mlambo, G., Barbet, A.F., Mahan, S.M.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Cambridge University Press 1999
Materias:
Acceso en línea:https://hdl.handle.net/10568/28497
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author Peter, T.F.
Perry, Brian D.
O'Callaghan, C.J.
Medley, G.F.
Mlambo, G.
Barbet, A.F.
Mahan, S.M.
author_browse Barbet, A.F.
Mahan, S.M.
Medley, G.F.
Mlambo, G.
O'Callaghan, C.J.
Perry, Brian D.
Peter, T.F.
author_facet Peter, T.F.
Perry, Brian D.
O'Callaghan, C.J.
Medley, G.F.
Mlambo, G.
Barbet, A.F.
Mahan, S.M.
author_sort Peter, T.F.
collection Repository of Agricultural Research Outputs (CGSpace)
description Analysis of the transmission dynamics of Cowdria ruminantium, the tick-borne rickettsial agent of heartwater in ruminants, requires accurate measures of infection in vector populations. To obtain these, Amblyomma hebraeum ticks were collected at two heartwater-endemic locations in the lowveld and highveld regions of Zimbabwe and assessed for C. ruminantium infection with specific polymerase chain reaction (PCR) and DNA probe detection assays. At the lowveld site, 11±2% (50}446) of adult ticks and 8±5% (23}271) of nymphs carried C. ruminantium, as detected by PCR. At the highveld site, the prevalence of infection in adult ticks was 10±2% (40}392). DNA probe analysis revealed that most infections at both sites were of low intensity ; only 9% and 23% of all nymph and adult tick infections, respectively, were greater than 70000 organisms, the detection limit of the DNA probe. However, the majority (70%) of probedetectable adult tick infections were high, between 10( and 10* organisms}tick, while those within nymphs were lower, between 10& and 10' organisms}tick.
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spelling CGSpace284972024-11-15T08:52:46Z Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe Peter, T.F. Perry, Brian D. O'Callaghan, C.J. Medley, G.F. Mlambo, G. Barbet, A.F. Mahan, S.M. cowdria ruminantium morbidity amblyomma hebraeum metastigmata bacterial diseases endemics isolation culture media pcr Analysis of the transmission dynamics of Cowdria ruminantium, the tick-borne rickettsial agent of heartwater in ruminants, requires accurate measures of infection in vector populations. To obtain these, Amblyomma hebraeum ticks were collected at two heartwater-endemic locations in the lowveld and highveld regions of Zimbabwe and assessed for C. ruminantium infection with specific polymerase chain reaction (PCR) and DNA probe detection assays. At the lowveld site, 11±2% (50}446) of adult ticks and 8±5% (23}271) of nymphs carried C. ruminantium, as detected by PCR. At the highveld site, the prevalence of infection in adult ticks was 10±2% (40}392). DNA probe analysis revealed that most infections at both sites were of low intensity ; only 9% and 23% of all nymph and adult tick infections, respectively, were greater than 70000 organisms, the detection limit of the DNA probe. However, the majority (70%) of probedetectable adult tick infections were high, between 10( and 10* organisms}tick, while those within nymphs were lower, between 10& and 10' organisms}tick. 1999-10 2013-05-06T07:00:43Z 2013-05-06T07:00:43Z Journal Article https://hdl.handle.net/10568/28497 en Open Access Cambridge University Press Epidemiology and Infection;123(2): 309-316
spellingShingle cowdria ruminantium
morbidity
amblyomma hebraeum
metastigmata
bacterial diseases
endemics
isolation
culture media
pcr
Peter, T.F.
Perry, Brian D.
O'Callaghan, C.J.
Medley, G.F.
Mlambo, G.
Barbet, A.F.
Mahan, S.M.
Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
title Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
title_full Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
title_fullStr Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
title_full_unstemmed Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
title_short Prevalence of Cowdria ruminantium infection in Amblyomma hebraeum ticks from heartwater-endemic areas of Zimbabwe
title_sort prevalence of cowdria ruminantium infection in amblyomma hebraeum ticks from heartwater endemic areas of zimbabwe
topic cowdria ruminantium
morbidity
amblyomma hebraeum
metastigmata
bacterial diseases
endemics
isolation
culture media
pcr
url https://hdl.handle.net/10568/28497
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