The shared frailty model and the power for heterogeneity tests in multicenter trials

Heterogeneity between centers in multicenter trials with time to event outcome can be modeled by the frailty proportional hazards model. The majority of the different approaches that have been used to fit frailty models assume either the gamma or the lognormal frailty density and are based on simila...

Full description

Bibliographic Details
Main Authors: Duchateau, L., Janssen, P., Lindsey, P., Legrand, C., Nguti, R., Sylvester-Bradley, Rosemary
Format: Journal Article
Language:Inglés
Published: Elsevier 2002
Subjects:
Online Access:https://hdl.handle.net/10568/28432

Similar Items: The shared frailty model and the power for heterogeneity tests in multicenter trials