Radiation hybrid maps of candidate trypanotolerance regions in cattle
A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between catt...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
1999
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/28363 |
| _version_ | 1855524199850835968 |
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| author | Nilsson, P.H. Kang'a, S. Rottengatter, K. Suedbeck, U. Iraqui, F. Mwakaya, J. Mwangi, D. Womack, J.E. Goldammer, T. Schwerin, M. Bradley, D. Agaba, Morris Sugimoto, K. Gelhaus, A. Horstmann, R. Teale, A.J. Kemp, Stephen J. Hanotte, Olivier H. |
| author_browse | Agaba, Morris Bradley, D. Gelhaus, A. Goldammer, T. Hanotte, Olivier H. Horstmann, R. Iraqui, F. Kang'a, S. Kemp, Stephen J. Mwakaya, J. Mwangi, D. Nilsson, P.H. Rottengatter, K. Schwerin, M. Suedbeck, U. Sugimoto, K. Teale, A.J. Womack, J.E. |
| author_facet | Nilsson, P.H. Kang'a, S. Rottengatter, K. Suedbeck, U. Iraqui, F. Mwakaya, J. Mwangi, D. Womack, J.E. Goldammer, T. Schwerin, M. Bradley, D. Agaba, Morris Sugimoto, K. Gelhaus, A. Horstmann, R. Teale, A.J. Kemp, Stephen J. Hanotte, Olivier H. |
| author_sort | Nilsson, P.H. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between cattle, human and mice. Using a cattle radiation hybrid panel, first framework maps are constructed with type II markers (microsatellites). Then, type I markers (genes) are positioned within these maps. Their relative chromosomal positions, compared to their positions in human and mice, allow us to define conserved syntenic regions between the three species. The large number of genes being identified in human and mice may assist selection of candidate genes. |
| format | Journal Article |
| id | CGSpace28363 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1999 |
| publishDateRange | 1999 |
| publishDateSort | 1999 |
| record_format | dspace |
| spelling | CGSpace283632023-04-20T00:29:35Z Radiation hybrid maps of candidate trypanotolerance regions in cattle Nilsson, P.H. Kang'a, S. Rottengatter, K. Suedbeck, U. Iraqui, F. Mwakaya, J. Mwangi, D. Womack, J.E. Goldammer, T. Schwerin, M. Bradley, D. Agaba, Morris Sugimoto, K. Gelhaus, A. Horstmann, R. Teale, A.J. Kemp, Stephen J. Hanotte, Olivier H. trypanosomiasis disease resistance chromosomes cattle genetic maps A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between cattle, human and mice. Using a cattle radiation hybrid panel, first framework maps are constructed with type II markers (microsatellites). Then, type I markers (genes) are positioned within these maps. Their relative chromosomal positions, compared to their positions in human and mice, allow us to define conserved syntenic regions between the three species. The large number of genes being identified in human and mice may assist selection of candidate genes. 1999 2013-05-06T07:00:28Z 2013-05-06T07:00:28Z Journal Article https://hdl.handle.net/10568/28363 en Limited Access Archiv fur Tierzucht - Special Issue;42: 123-125 |
| spellingShingle | trypanosomiasis disease resistance chromosomes cattle genetic maps Nilsson, P.H. Kang'a, S. Rottengatter, K. Suedbeck, U. Iraqui, F. Mwakaya, J. Mwangi, D. Womack, J.E. Goldammer, T. Schwerin, M. Bradley, D. Agaba, Morris Sugimoto, K. Gelhaus, A. Horstmann, R. Teale, A.J. Kemp, Stephen J. Hanotte, Olivier H. Radiation hybrid maps of candidate trypanotolerance regions in cattle |
| title | Radiation hybrid maps of candidate trypanotolerance regions in cattle |
| title_full | Radiation hybrid maps of candidate trypanotolerance regions in cattle |
| title_fullStr | Radiation hybrid maps of candidate trypanotolerance regions in cattle |
| title_full_unstemmed | Radiation hybrid maps of candidate trypanotolerance regions in cattle |
| title_short | Radiation hybrid maps of candidate trypanotolerance regions in cattle |
| title_sort | radiation hybrid maps of candidate trypanotolerance regions in cattle |
| topic | trypanosomiasis disease resistance chromosomes cattle genetic maps |
| url | https://hdl.handle.net/10568/28363 |
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