Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance

We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolerance...

Full description

Bibliographic Details
Main Authors: Park, S.D.E., Adomefa, K., Dao, B., Hanotte, Olivier H., Kemp, Stephen J., Sow, R.S., Teale, A.J., Bradley, D.G.
Format: Journal Article
Language:Inglés
Published: 1999
Subjects:
Online Access:https://hdl.handle.net/10568/28361
_version_ 1855527930984136704
author Park, S.D.E.
Adomefa, K.
Dao, B.
Hanotte, Olivier H.
Kemp, Stephen J.
Sow, R.S.
Teale, A.J.
Bradley, D.G.
author_browse Adomefa, K.
Bradley, D.G.
Dao, B.
Hanotte, Olivier H.
Kemp, Stephen J.
Park, S.D.E.
Sow, R.S.
Teale, A.J.
author_facet Park, S.D.E.
Adomefa, K.
Dao, B.
Hanotte, Olivier H.
Kemp, Stephen J.
Sow, R.S.
Teale, A.J.
Bradley, D.G.
author_sort Park, S.D.E.
collection Repository of Agricultural Research Outputs (CGSpace)
description We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolerance. Population genetic analysis is used with mapped microsatellites to try to infer selection for trypanotolerance in West African cattle populations.
format Journal Article
id CGSpace28361
institution CGIAR Consortium
language Inglés
publishDate 1999
publishDateRange 1999
publishDateSort 1999
record_format dspace
spelling CGSpace283612023-04-20T00:29:35Z Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance Park, S.D.E. Adomefa, K. Dao, B. Hanotte, Olivier H. Kemp, Stephen J. Sow, R.S. Teale, A.J. Bradley, D.G. population genetics genetic maps selection disease resistance trypanosomiasis cattle genetic markers heterozygotes genetic distance We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolerance. Population genetic analysis is used with mapped microsatellites to try to infer selection for trypanotolerance in West African cattle populations. 1999 2013-05-06T07:00:28Z 2013-05-06T07:00:28Z Journal Article https://hdl.handle.net/10568/28361 en Limited Access Archiv fur Tierzucht - Special Issue;42: 97-99
spellingShingle population genetics
genetic maps
selection
disease resistance
trypanosomiasis
cattle
genetic markers
heterozygotes
genetic distance
Park, S.D.E.
Adomefa, K.
Dao, B.
Hanotte, Olivier H.
Kemp, Stephen J.
Sow, R.S.
Teale, A.J.
Bradley, D.G.
Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
title Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
title_full Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
title_fullStr Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
title_full_unstemmed Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
title_short Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
title_sort application of population genetic analysis of linked mapped microsatellites to the identification of loci under selection for disease resistance
topic population genetics
genetic maps
selection
disease resistance
trypanosomiasis
cattle
genetic markers
heterozygotes
genetic distance
url https://hdl.handle.net/10568/28361
work_keys_str_mv AT parksde applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT adomefak applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT daob applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT hanotteolivierh applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT kempstephenj applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT sowrs applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT tealeaj applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance
AT bradleydg applicationofpopulationgeneticanalysisoflinkedmappedmicrosatellitestotheidentificationoflociunderselectionfordiseaseresistance