Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva
The initial studies of the products of the bovine MHC with alloraective T lymphocytes generated in vitro have been described. In those studies, the cytolytic activity and specificity of bulk populations of alloreactive T cells were investigated. One non-cytolytic and two cytolytic BoT4 + clones were...
| Main Authors: | , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
1988
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/28244 |
| _version_ | 1855519924236058624 |
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| author | Teale, A.J. Baldwin, Cynthia L. |
| author_browse | Baldwin, Cynthia L. Teale, A.J. |
| author_facet | Teale, A.J. Baldwin, Cynthia L. |
| author_sort | Teale, A.J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The initial studies of the products of the bovine MHC with alloraective T lymphocytes generated in vitro have been described. In those studies, the cytolytic activity and specificity of bulk populations of alloreactive T cells were investigated. One non-cytolytic and two cytolytic BoT4 + clones were studied following in vitro infection and transformation with sporozoites of T. parva. In this paper, the results of this study are also discussed. According to the results, transformation of bovine alloreactive T lymphocytes has the advantage that derived cell lines do not require repeated exposure to antigen and the addition of exogenons growth factors during culture and thus are simple to maintain in a functional state. |
| format | Journal Article |
| id | CGSpace28244 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1988 |
| publishDateRange | 1988 |
| publishDateSort | 1988 |
| record_format | dspace |
| spelling | CGSpace282442024-01-17T12:58:34Z Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva Teale, A.J. Baldwin, Cynthia L. theileria parva animal diseases metastigmata lymphocytes The initial studies of the products of the bovine MHC with alloraective T lymphocytes generated in vitro have been described. In those studies, the cytolytic activity and specificity of bulk populations of alloreactive T cells were investigated. One non-cytolytic and two cytolytic BoT4 + clones were studied following in vitro infection and transformation with sporozoites of T. parva. In this paper, the results of this study are also discussed. According to the results, transformation of bovine alloreactive T lymphocytes has the advantage that derived cell lines do not require repeated exposure to antigen and the addition of exogenons growth factors during culture and thus are simple to maintain in a functional state. 1988 2013-05-06T07:00:13Z 2013-05-06T07:00:13Z Journal Article https://hdl.handle.net/10568/28244 en Limited Access Animal genetics;19: 30-31 |
| spellingShingle | theileria parva animal diseases metastigmata lymphocytes Teale, A.J. Baldwin, Cynthia L. Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva |
| title | Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva |
| title_full | Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva |
| title_fullStr | Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva |
| title_full_unstemmed | Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva |
| title_short | Functional aspects of BoT4+ alloreactive T lymphocytes transformed by Theileria parva |
| title_sort | functional aspects of bot4 alloreactive t lymphocytes transformed by theileria parva |
| topic | theileria parva animal diseases metastigmata lymphocytes |
| url | https://hdl.handle.net/10568/28244 |
| work_keys_str_mv | AT tealeaj functionalaspectsofbot4alloreactivetlymphocytestransformedbytheileriaparva AT baldwincynthial functionalaspectsofbot4alloreactivetlymphocytestransformedbytheileriaparva |