PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle

A study of polymorphisms of mitochondrial DNA (mtDNA) of West African N'Dama (Bos taurus) and East African Zebu (B. indicus) cattle was carried out to obtain information on maternal phylogenetic relationships between these breeds. A relatively large sample size was made possible by using polymerase...

Full description

Bibliographic Details
Main Authors: Suzuki, R., Kemp, Stephen J., Teale, A.J.
Format: Journal Article
Language:Inglés
Published: Wiley 1992
Subjects:
Online Access:https://hdl.handle.net/10568/28225
_version_ 1855539859235536896
author Suzuki, R.
Kemp, Stephen J.
Teale, A.J.
author_browse Kemp, Stephen J.
Suzuki, R.
Teale, A.J.
author_facet Suzuki, R.
Kemp, Stephen J.
Teale, A.J.
author_sort Suzuki, R.
collection Repository of Agricultural Research Outputs (CGSpace)
description A study of polymorphisms of mitochondrial DNA (mtDNA) of West African N'Dama (Bos taurus) and East African Zebu (B. indicus) cattle was carried out to obtain information on maternal phylogenetic relationships between these breeds. A relatively large sample size was made possible by using polymerase chain reaction (PCR) amplification of DNA prepared from small blood samples to generate fragments of two known polymorphic mtDNA regions, one within the gene encoding subunit 5 of NADH dehydrogenase and one encompassing the entire D‐loop. This approach allowed us to achieve a higher resolution restriction analysis on mtDNA from more animals than would have been possible by conventional methods. PCR‐amplified mtDNA of 58 animals from five populations was examined at 26 restriction sites by 16 enzymes. In this way 154 nucleotides of mtDNA were scanned for polymorphism. Six polymorphic sites were located by this means, five of which were within the D‐loop and one of which was within the NADH dehydrogenase 5 gene. None of the polymorphisms observed could be con sidered typical of breed or type.
format Journal Article
id CGSpace28225
institution CGIAR Consortium
language Inglés
publishDate 1992
publishDateRange 1992
publishDateSort 1992
publisher Wiley
publisherStr Wiley
record_format dspace
spelling CGSpace282252024-08-27T10:37:11Z PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle Suzuki, R. Kemp, Stephen J. Teale, A.J. zebu cattle ndama cattle dna mitochondria A study of polymorphisms of mitochondrial DNA (mtDNA) of West African N'Dama (Bos taurus) and East African Zebu (B. indicus) cattle was carried out to obtain information on maternal phylogenetic relationships between these breeds. A relatively large sample size was made possible by using polymerase chain reaction (PCR) amplification of DNA prepared from small blood samples to generate fragments of two known polymorphic mtDNA regions, one within the gene encoding subunit 5 of NADH dehydrogenase and one encompassing the entire D‐loop. This approach allowed us to achieve a higher resolution restriction analysis on mtDNA from more animals than would have been possible by conventional methods. PCR‐amplified mtDNA of 58 animals from five populations was examined at 26 restriction sites by 16 enzymes. In this way 154 nucleotides of mtDNA were scanned for polymorphism. Six polymorphic sites were located by this means, five of which were within the D‐loop and one of which was within the NADH dehydrogenase 5 gene. None of the polymorphisms observed could be con sidered typical of breed or type. 1992 2013-05-06T07:00:11Z 2013-05-06T07:00:11Z Journal Article https://hdl.handle.net/10568/28225 en Limited Access Wiley Animal Genetics;23(Suppl. 1): 62
spellingShingle zebu cattle
ndama cattle
dna
mitochondria
Suzuki, R.
Kemp, Stephen J.
Teale, A.J.
PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
title PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
title_full PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
title_fullStr PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
title_full_unstemmed PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
title_short PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
title_sort pcr analysis of mitochondrial dna polymorphism in n dama and zebu cattle
topic zebu cattle
ndama cattle
dna
mitochondria
url https://hdl.handle.net/10568/28225
work_keys_str_mv AT suzukir pcranalysisofmitochondrialdnapolymorphisminndamaandzebucattle
AT kempstephenj pcranalysisofmitochondrialdnapolymorphisminndamaandzebucattle
AT tealeaj pcranalysisofmitochondrialdnapolymorphisminndamaandzebucattle