Introduction to the BoLA system
This paper reviews papers that deals with bovine lymphocyte antigen (BoLA) system. It discusses when characterization of the bovine MHC began, workshops conducted and their concerns which included serological characterization of the products of the MHC, the bovine lymphocyte antigen (BoLA) system, u...
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
1988
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| Acceso en línea: | https://hdl.handle.net/10568/28221 |
| _version_ | 1855531806521032704 |
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| author | Teale, A.J. |
| author_browse | Teale, A.J. |
| author_facet | Teale, A.J. |
| author_sort | Teale, A.J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | This paper reviews papers that deals with bovine lymphocyte antigen (BoLA) system. It discusses when characterization of the bovine MHC began, workshops conducted and their concerns which included serological characterization of the products of the MHC, the bovine lymphocyte antigen (BoLA) system, using alloantisera from a number of laboratories in a microlymphocy toxicity screen on cells from dornor cattle available in Edinburgh. The paper also discusses the expression in cattle of a second or even a third BoLA class I locus, number and nature of expressed bovine class I gene products, and the complexicity of the BoLA class I system. Examines early attempts made to define bovine class II antigens involved assays of mixed lymphocyte reactivity. It also put the description given by Andersson (1986) on the use of heterologus DNA probes for RFLP analysis of the bovine class II polymorphisms at the level of the genome. The paper also discusses the attempts made in the laboratory to produce murine mAb to bovine class II determinants. |
| format | Journal Article |
| id | CGSpace28221 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1988 |
| publishDateRange | 1988 |
| publishDateSort | 1988 |
| record_format | dspace |
| spelling | CGSpace282212022-01-29T16:02:17Z Introduction to the BoLA system Teale, A.J. animal diseases bovinae lymphocytes antigens This paper reviews papers that deals with bovine lymphocyte antigen (BoLA) system. It discusses when characterization of the bovine MHC began, workshops conducted and their concerns which included serological characterization of the products of the MHC, the bovine lymphocyte antigen (BoLA) system, using alloantisera from a number of laboratories in a microlymphocy toxicity screen on cells from dornor cattle available in Edinburgh. The paper also discusses the expression in cattle of a second or even a third BoLA class I locus, number and nature of expressed bovine class I gene products, and the complexicity of the BoLA class I system. Examines early attempts made to define bovine class II antigens involved assays of mixed lymphocyte reactivity. It also put the description given by Andersson (1986) on the use of heterologus DNA probes for RFLP analysis of the bovine class II polymorphisms at the level of the genome. The paper also discusses the attempts made in the laboratory to produce murine mAb to bovine class II determinants. 1988 2013-05-06T07:00:10Z 2013-05-06T07:00:10Z Journal Article https://hdl.handle.net/10568/28221 en Limited Access Animal Genetics;19(suppl. 1): 1-4 |
| spellingShingle | animal diseases bovinae lymphocytes antigens Teale, A.J. Introduction to the BoLA system |
| title | Introduction to the BoLA system |
| title_full | Introduction to the BoLA system |
| title_fullStr | Introduction to the BoLA system |
| title_full_unstemmed | Introduction to the BoLA system |
| title_short | Introduction to the BoLA system |
| title_sort | introduction to the bola system |
| topic | animal diseases bovinae lymphocytes antigens |
| url | https://hdl.handle.net/10568/28221 |
| work_keys_str_mv | AT tealeaj introductiontothebolasystem |