A comparative study of major histocompatibility complex antigens in East African and European cattle breeds
Summary.An account is given of the serologically defined class I specificities encoded by the bovine MHC (expressed as the BoLA system) in two populations of African cattle and in European breeds.The BoLA typing was performed using alloantisera raised against tissue antigens of both European and Afr...
| Main Authors: | , , |
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| Format: | Journal Article |
| Language: | Inglés |
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Wiley
1988
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/28216 |
| _version_ | 1855535165923655680 |
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| author | Kemp, Stephen J. Spooner, R.L. Teale, A.J. |
| author_browse | Kemp, Stephen J. Spooner, R.L. Teale, A.J. |
| author_facet | Kemp, Stephen J. Spooner, R.L. Teale, A.J. |
| author_sort | Kemp, Stephen J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Summary.An account is given of the serologically defined class I specificities encoded by the bovine MHC (expressed as the BoLA system) in two populations of African cattle and in European breeds.The BoLA typing was performed using alloantisera raised against tissue antigens of both European and African breeds of cattle. All of the specificities agreed in the first two international BoLA workshops were found in the African cattle, although there were significant differences in the frequency of some specificities between the African and European animals. Many of the European antisera, which are operationally monospecific in Bos taurus cattle, were multispecific in the African animals.Subgroups of two specificities (w8 and w10) were demonstrated. Five new BoLA‐A locus alleles were detected by means of antisera raised against alloantigens of African cattle. Two of these occurred at an extremely high frequency in the African populations; one being unique to these cattle. Monoclonal antibodies proved to be useful typing reagents, particularly in the elucidation of subgroups. |
| format | Journal Article |
| id | CGSpace28216 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 1988 |
| publishDateRange | 1988 |
| publishDateSort | 1988 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | CGSpace282162024-05-01T08:18:53Z A comparative study of major histocompatibility complex antigens in East African and European cattle breeds Kemp, Stephen J. Spooner, R.L. Teale, A.J. europe antigens cattle breeds major histocompatibility complex Summary.An account is given of the serologically defined class I specificities encoded by the bovine MHC (expressed as the BoLA system) in two populations of African cattle and in European breeds.The BoLA typing was performed using alloantisera raised against tissue antigens of both European and African breeds of cattle. All of the specificities agreed in the first two international BoLA workshops were found in the African cattle, although there were significant differences in the frequency of some specificities between the African and European animals. Many of the European antisera, which are operationally monospecific in Bos taurus cattle, were multispecific in the African animals.Subgroups of two specificities (w8 and w10) were demonstrated. Five new BoLA‐A locus alleles were detected by means of antisera raised against alloantigens of African cattle. Two of these occurred at an extremely high frequency in the African populations; one being unique to these cattle. Monoclonal antibodies proved to be useful typing reagents, particularly in the elucidation of subgroups. 1988 2013-05-06T07:00:10Z 2013-05-06T07:00:10Z Journal Article https://hdl.handle.net/10568/28216 en Limited Access Wiley Animal Genetics;19: 17-29 |
| spellingShingle | europe antigens cattle breeds major histocompatibility complex Kemp, Stephen J. Spooner, R.L. Teale, A.J. A comparative study of major histocompatibility complex antigens in East African and European cattle breeds |
| title | A comparative study of major histocompatibility complex antigens in East African and European cattle breeds |
| title_full | A comparative study of major histocompatibility complex antigens in East African and European cattle breeds |
| title_fullStr | A comparative study of major histocompatibility complex antigens in East African and European cattle breeds |
| title_full_unstemmed | A comparative study of major histocompatibility complex antigens in East African and European cattle breeds |
| title_short | A comparative study of major histocompatibility complex antigens in East African and European cattle breeds |
| title_sort | comparative study of major histocompatibility complex antigens in east african and european cattle breeds |
| topic | europe antigens cattle breeds major histocompatibility complex |
| url | https://hdl.handle.net/10568/28216 |
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