| Sumario: | We report on the results of work on three bacterial zoonoses arising as part of a large project dealing with
zoonotic infections amongst livestock and the farmers who keep them. Domestic livestock are an important
source of zoonotic infections to humans, particularly in rural parts of Africa. Understanding the interactions
between people and their domestic animals, and the transmission of zoonoses between them, is of vital
importance in creating the evidence-based disease control policies that are required to protect both human
and animal health. The wider project addresses the impact of co-factors (a condition that influences the
effects of another condition) on the epidemiology of, and burden imposed by, these diseases. We describe
the results of an analysis of three bacterial infections of major public health significance (q-fever, brucellosis
and tuberculosis), with a focus on infection in both domestic cattle and humans. In particular, we explore the
spatial distribution of these infections in Western Kenya, and explore patterns of infection at the household
level in both species (n=450 households). In addition, using multivariate methods, we examine non-zoonotic
co-factors as explanatory variables for the individual pathogens, and quantify the risk of co-infections with
multiple bacterial zoonoses. We use our wealth of ancillary risk factor data to explain the patterns observed.
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