Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background
Differences in gene expression may be caused by nearby DNA polymorphisms (cis regulation) or by interactions of gene control regions with polymorphic transcription factors (trans regulation). Trans acting loci are much harder to detect than cis acting loci and their effects are much more sensitive t...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Springer
2010
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/2324 |
| _version_ | 1855532832410042368 |
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| author | Noyes, H.A. Agaba, Morris Anderson, S. Archibald, A.L. Brass, A. Gibson, John P. Hall, L. Hulme, H. Oh, S.J. Kemp, Stephen J. |
| author_browse | Agaba, Morris Anderson, S. Archibald, A.L. Brass, A. Gibson, John P. Hall, L. Hulme, H. Kemp, Stephen J. Noyes, H.A. Oh, S.J. |
| author_facet | Noyes, H.A. Agaba, Morris Anderson, S. Archibald, A.L. Brass, A. Gibson, John P. Hall, L. Hulme, H. Oh, S.J. Kemp, Stephen J. |
| author_sort | Noyes, H.A. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Differences in gene expression may be caused by nearby DNA polymorphisms (cis regulation) or by interactions of gene control regions with polymorphic transcription factors (trans regulation). Trans acting loci are much harder to detect than cis acting loci and their effects are much more sensitive to genetic background. |
| format | Journal Article |
| id | CGSpace2324 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2010 |
| publishDateRange | 2010 |
| publishDateSort | 2010 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace23242024-05-01T08:18:35Z Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background Noyes, H.A. Agaba, Morris Anderson, S. Archibald, A.L. Brass, A. Gibson, John P. Hall, L. Hulme, H. Oh, S.J. Kemp, Stephen J. genetics mice Differences in gene expression may be caused by nearby DNA polymorphisms (cis regulation) or by interactions of gene control regions with polymorphic transcription factors (trans regulation). Trans acting loci are much harder to detect than cis acting loci and their effects are much more sensitive to genetic background. 2010-12 2010-08-23T15:08:51Z 2010-08-23T15:08:51Z Journal Article https://hdl.handle.net/10568/2324 en Open Access Springer Noyes, H.A.; Agaba, M.; Anderson, S.; Archibald, A.L.; Brass, A.; Gibson, J.; Hall, L.; Hulme, H.; Oh, S.J.; Kemp, S. 2010. Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background. BMC Genomics 11:361. |
| spellingShingle | genetics mice Noyes, H.A. Agaba, Morris Anderson, S. Archibald, A.L. Brass, A. Gibson, John P. Hall, L. Hulme, H. Oh, S.J. Kemp, Stephen J. Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| title | Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| title_full | Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| title_fullStr | Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| title_full_unstemmed | Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| title_short | Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| title_sort | genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background |
| topic | genetics mice |
| url | https://hdl.handle.net/10568/2324 |
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