Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays
Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to affe...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Springer
2008
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/2202 |
| _version_ | 1855536698096615424 |
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| author | Rennie, C. Noyes, H.A. Kemp, Stephen J. Hulme, H. Brass, A. Hoyle, D.C. |
| author_browse | Brass, A. Hoyle, D.C. Hulme, H. Kemp, Stephen J. Noyes, H.A. Rennie, C. |
| author_facet | Rennie, C. Noyes, H.A. Kemp, Stephen J. Hulme, H. Brass, A. Hoyle, D.C. |
| author_sort | Rennie, C. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to affect the stability of the probe-target duplex, and hence the strength of the observed signals from microarrays. |
| format | Journal Article |
| id | CGSpace2202 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2008 |
| publishDateRange | 2008 |
| publishDateSort | 2008 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace22022024-05-01T08:19:08Z Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays Rennie, C. Noyes, H.A. Kemp, Stephen J. Hulme, H. Brass, A. Hoyle, D.C. genetics livestock Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to affect the stability of the probe-target duplex, and hence the strength of the observed signals from microarrays. 2008-12 2010-08-07T12:07:26Z 2010-08-07T12:07:26Z Journal Article https://hdl.handle.net/10568/2202 en Open Access Springer Rennie, C.; Noyes, H.A.; Kemp, S.J.; Hulme, H.; Brass, A.; Hoyle, D.C. 2008. Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays. BMC Genomics 9:317. |
| spellingShingle | genetics livestock Rennie, C. Noyes, H.A. Kemp, Stephen J. Hulme, H. Brass, A. Hoyle, D.C. Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| title | Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| title_full | Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| title_fullStr | Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| title_full_unstemmed | Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| title_short | Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| title_sort | strong position dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays |
| topic | genetics livestock |
| url | https://hdl.handle.net/10568/2202 |
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