Genome of the host-cell transforming parasite Theileria annulata compared with T. parva
Theileria annulata and T. parva are closely related protozoan parasites that cause lymphoproliferative diseases of cattle. We sequenced the genome of T. annulata and compared it with that of T. parva to understand the mechanisms underlying transformation and tropism. Despite high conservation of gen...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
American Association for the Advancement of Science
2005
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/21171 |
| _version_ | 1855532870003589120 |
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| author | Pain, A. Renauld, H. Berriman, M. Murphy, L. Yeats, C.A. Weir, W. Kerhornou, A. Aslett, M. Bishop, Richard P. Bouchier, C. Cochet, M. Coulson, R.M.R. Cronin, A. Villiers, Etienne P. de Fraser, A. Fosker, N. Gardner, M. Goble, A. Griffiths-Jones, S. Harris, D.E. Katzer, F. Larke, N. Lord, A. Maser, P. McKellar, S. Mooney, P. Morton, F. Nene, Vishvanath M. O'Neil, S. Price, C. Quail, M.A. Rabbinowitsch, E. Rawlings, N.D. Rutter, S. Saunders, D. Seeger, K. Shah, Tushaar Squares, R. Squares, S. Tivey, A. Walker, A.R. Woodward, J. Dobbelaere, D.A.E. Langsley, G. Rajandream, M.A. McKeever, Declan J. Shiels, B. Tait, A. Barrell, B. Hall, N. |
| author_browse | Aslett, M. Barrell, B. Berriman, M. Bishop, Richard P. Bouchier, C. Cochet, M. Coulson, R.M.R. Cronin, A. Dobbelaere, D.A.E. Fosker, N. Fraser, A. Gardner, M. Goble, A. Griffiths-Jones, S. Hall, N. Harris, D.E. Katzer, F. Kerhornou, A. Langsley, G. Larke, N. Lord, A. Maser, P. McKeever, Declan J. McKellar, S. Mooney, P. Morton, F. Murphy, L. Nene, Vishvanath M. O'Neil, S. Pain, A. Price, C. Quail, M.A. Rabbinowitsch, E. Rajandream, M.A. Rawlings, N.D. Renauld, H. Rutter, S. Saunders, D. Seeger, K. Shah, Tushaar Shiels, B. Squares, R. Squares, S. Tait, A. Tivey, A. Villiers, Etienne P. de Walker, A.R. Weir, W. Woodward, J. Yeats, C.A. |
| author_facet | Pain, A. Renauld, H. Berriman, M. Murphy, L. Yeats, C.A. Weir, W. Kerhornou, A. Aslett, M. Bishop, Richard P. Bouchier, C. Cochet, M. Coulson, R.M.R. Cronin, A. Villiers, Etienne P. de Fraser, A. Fosker, N. Gardner, M. Goble, A. Griffiths-Jones, S. Harris, D.E. Katzer, F. Larke, N. Lord, A. Maser, P. McKellar, S. Mooney, P. Morton, F. Nene, Vishvanath M. O'Neil, S. Price, C. Quail, M.A. Rabbinowitsch, E. Rawlings, N.D. Rutter, S. Saunders, D. Seeger, K. Shah, Tushaar Squares, R. Squares, S. Tivey, A. Walker, A.R. Woodward, J. Dobbelaere, D.A.E. Langsley, G. Rajandream, M.A. McKeever, Declan J. Shiels, B. Tait, A. Barrell, B. Hall, N. |
| author_sort | Pain, A. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Theileria annulata and T. parva are closely related protozoan parasites that cause lymphoproliferative diseases of cattle. We sequenced the genome of T. annulata and compared it with that of T. parva to understand the mechanisms underlying transformation and tropism. Despite high conservation of gene sequences and synteny, the analysis reveals unequally expanded gene families and species-specific genes. We also identify divergent families of putative secreted polypeptides that may reduce immune recognition, candidate regulators of host-cell transformation, and a Theileria-specific protein domain [frequently associated in Theileria (FAINT)] present in a large number of secreted proteins. |
| format | Journal Article |
| id | CGSpace21171 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2005 |
| publishDateRange | 2005 |
| publishDateSort | 2005 |
| publisher | American Association for the Advancement of Science |
| publisherStr | American Association for the Advancement of Science |
| record_format | dspace |
| spelling | CGSpace211712025-11-13T10:39:01Z Genome of the host-cell transforming parasite Theileria annulata compared with T. parva Pain, A. Renauld, H. Berriman, M. Murphy, L. Yeats, C.A. Weir, W. Kerhornou, A. Aslett, M. Bishop, Richard P. Bouchier, C. Cochet, M. Coulson, R.M.R. Cronin, A. Villiers, Etienne P. de Fraser, A. Fosker, N. Gardner, M. Goble, A. Griffiths-Jones, S. Harris, D.E. Katzer, F. Larke, N. Lord, A. Maser, P. McKellar, S. Mooney, P. Morton, F. Nene, Vishvanath M. O'Neil, S. Price, C. Quail, M.A. Rabbinowitsch, E. Rawlings, N.D. Rutter, S. Saunders, D. Seeger, K. Shah, Tushaar Squares, R. Squares, S. Tivey, A. Walker, A.R. Woodward, J. Dobbelaere, D.A.E. Langsley, G. Rajandream, M.A. McKeever, Declan J. Shiels, B. Tait, A. Barrell, B. Hall, N. parasites theileria annulata theileria parva genome hosts cell Theileria annulata and T. parva are closely related protozoan parasites that cause lymphoproliferative diseases of cattle. We sequenced the genome of T. annulata and compared it with that of T. parva to understand the mechanisms underlying transformation and tropism. Despite high conservation of gene sequences and synteny, the analysis reveals unequally expanded gene families and species-specific genes. We also identify divergent families of putative secreted polypeptides that may reduce immune recognition, candidate regulators of host-cell transformation, and a Theileria-specific protein domain [frequently associated in Theileria (FAINT)] present in a large number of secreted proteins. 2005-07 2012-07-09T05:42:17Z 2012-07-09T05:42:17Z Journal Article https://hdl.handle.net/10568/21171 en Limited Access American Association for the Advancement of Science Pain, A., Renauld, H., Berriman, M., Murphy, L., Yeats, C. A., Weir, W., Kerhornou, A., Aslett, M., Bishop, R., Bouchier, C., Cochet, M., Coulson, R. M. R., Cronin, A., de Villiers, E. P., Fraser, A., Fosker, N., Gardner, M., Goble, A., Griffiths-Jones, S., … Hall, N. (2005). Genome of the Host-Cell Transforming Parasite Theileria annulata Compared with T. parva. Science, 309(5731), 131–133. https://doi.org/10.1126/science.1110418 |
| spellingShingle | parasites theileria annulata theileria parva genome hosts cell Pain, A. Renauld, H. Berriman, M. Murphy, L. Yeats, C.A. Weir, W. Kerhornou, A. Aslett, M. Bishop, Richard P. Bouchier, C. Cochet, M. Coulson, R.M.R. Cronin, A. Villiers, Etienne P. de Fraser, A. Fosker, N. Gardner, M. Goble, A. Griffiths-Jones, S. Harris, D.E. Katzer, F. Larke, N. Lord, A. Maser, P. McKellar, S. Mooney, P. Morton, F. Nene, Vishvanath M. O'Neil, S. Price, C. Quail, M.A. Rabbinowitsch, E. Rawlings, N.D. Rutter, S. Saunders, D. Seeger, K. Shah, Tushaar Squares, R. Squares, S. Tivey, A. Walker, A.R. Woodward, J. Dobbelaere, D.A.E. Langsley, G. Rajandream, M.A. McKeever, Declan J. Shiels, B. Tait, A. Barrell, B. Hall, N. Genome of the host-cell transforming parasite Theileria annulata compared with T. parva |
| title | Genome of the host-cell transforming parasite Theileria annulata compared with T. parva |
| title_full | Genome of the host-cell transforming parasite Theileria annulata compared with T. parva |
| title_fullStr | Genome of the host-cell transforming parasite Theileria annulata compared with T. parva |
| title_full_unstemmed | Genome of the host-cell transforming parasite Theileria annulata compared with T. parva |
| title_short | Genome of the host-cell transforming parasite Theileria annulata compared with T. parva |
| title_sort | genome of the host cell transforming parasite theileria annulata compared with t parva |
| topic | parasites theileria annulata theileria parva genome hosts cell |
| url | https://hdl.handle.net/10568/21171 |
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