Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds
The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to int...
| Autor principal: | |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
American Association for the Advancement of Science
2009
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/2020 |
| _version_ | 1855530415374204928 |
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| author | Bovine HapMap Consortium |
| author_browse | Bovine HapMap Consortium |
| author_facet | Bovine HapMap Consortium |
| author_sort | Bovine HapMap Consortium |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans. |
| format | Journal Article |
| id | CGSpace2020 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2009 |
| publishDateRange | 2009 |
| publishDateSort | 2009 |
| publisher | American Association for the Advancement of Science |
| publisherStr | American Association for the Advancement of Science |
| record_format | dspace |
| spelling | CGSpace20202023-12-08T19:36:04Z Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds Bovine HapMap Consortium genomes cattle The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans. 2009-04-24 2010-07-05T19:37:40Z 2010-07-05T19:37:40Z Journal Article https://hdl.handle.net/10568/2020 en Open Access American Association for the Advancement of Science Bovine HapMap Consortium. 2009. Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science 324(5926):528-532. |
| spellingShingle | genomes cattle Bovine HapMap Consortium Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds |
| title | Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds |
| title_full | Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds |
| title_fullStr | Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds |
| title_full_unstemmed | Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds |
| title_short | Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds |
| title_sort | genome wide survey of snp variation uncovers the genetic structure of cattle breeds |
| topic | genomes cattle |
| url | https://hdl.handle.net/10568/2020 |
| work_keys_str_mv | AT bovinehapmapconsortium genomewidesurveyofsnpvariationuncoversthegeneticstructureofcattlebreeds |