Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene
We report the mitochondrial DNA (mtDNA) characterization of 77 indigenous chickens (fighting and meat birds) from Madagascar, using DNA sequences of the first hypervariable segment of the D-loop. Comparison with reference samples from the African continent and Asia revealed two mtDNA haplogroups, su...
| Autores principales: | , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Wiley
2008
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/1882 |
| _version_ | 1855516856395235328 |
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| author | Razafindraibe, H. Mobegi, V.A. Ommeh, S.C. Ralptondravao Bjornstad, G. Hanotte, Olivier H. Han Jianlin |
| author_browse | Bjornstad, G. Han Jianlin Hanotte, Olivier H. Mobegi, V.A. Ommeh, S.C. Ralptondravao Razafindraibe, H. |
| author_facet | Razafindraibe, H. Mobegi, V.A. Ommeh, S.C. Ralptondravao Bjornstad, G. Hanotte, Olivier H. Han Jianlin |
| author_sort | Razafindraibe, H. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | We report the mitochondrial DNA (mtDNA) characterization of 77 indigenous chickens (fighting and meat birds) from Madagascar, using DNA sequences of the first hypervariable segment of the D-loop. Comparison with reference samples from the African continent and Asia revealed two mtDNA haplogroups, suggesting a dual geographic and genetic origin for the indigenous Malagasy chickens. The most common haplogroup was present in 65 individuals of the two types; it is likely of Indonesian origin. The second haplogroup was observed in 12 fighting birds and meat chickens; it could be of African continental origin and/or the result of recent introgression with commercial lines. We further studied a G/A single nucleotide polymorphism at nucleotide position 1892 bp of the coding sequence of the Mx gene that is reported to be one of the candidate susceptible/resistant genes to viral infection in chicken. Our results indicate the "susceptible" allele G is the most common with frequencies of 65% and 70% in Malagasy fighting and meat chickens, respectively. However, the allelic frequency difference between the two types of chickens is not significant (P > 0.05). These results are discussed in light of our current linguistic and archaeological knowledge on the origin of indigenous Malagasy chickens. |
| format | Journal Article |
| id | CGSpace1882 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2008 |
| publishDateRange | 2008 |
| publishDateSort | 2008 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | CGSpace18822024-11-15T08:52:11Z Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene Razafindraibe, H. Mobegi, V.A. Ommeh, S.C. Ralptondravao Bjornstad, G. Hanotte, Olivier H. Han Jianlin chickens madagascar We report the mitochondrial DNA (mtDNA) characterization of 77 indigenous chickens (fighting and meat birds) from Madagascar, using DNA sequences of the first hypervariable segment of the D-loop. Comparison with reference samples from the African continent and Asia revealed two mtDNA haplogroups, suggesting a dual geographic and genetic origin for the indigenous Malagasy chickens. The most common haplogroup was present in 65 individuals of the two types; it is likely of Indonesian origin. The second haplogroup was observed in 12 fighting birds and meat chickens; it could be of African continental origin and/or the result of recent introgression with commercial lines. We further studied a G/A single nucleotide polymorphism at nucleotide position 1892 bp of the coding sequence of the Mx gene that is reported to be one of the candidate susceptible/resistant genes to viral infection in chicken. Our results indicate the "susceptible" allele G is the most common with frequencies of 65% and 70% in Malagasy fighting and meat chickens, respectively. However, the allelic frequency difference between the two types of chickens is not significant (P > 0.05). These results are discussed in light of our current linguistic and archaeological knowledge on the origin of indigenous Malagasy chickens. 2008-12 2010-06-13T16:41:13Z 2010-06-13T16:41:13Z Journal Article https://hdl.handle.net/10568/1882 en Open Access Wiley Razafindraibe, H.; Mobegi, V.A.; Ommeh, S.C.; Ralptondravao, Bjørnstad, G.; Hanotte, O.; Jianlin, H. 2008. Mitochondrial DNA origin of indigenous Malagasy chickens: implication for a functional polymorphism of the Mx gene. The Annals of the New York Academy of Sciences 1149(1):77-79. |
| spellingShingle | chickens madagascar Razafindraibe, H. Mobegi, V.A. Ommeh, S.C. Ralptondravao Bjornstad, G. Hanotte, Olivier H. Han Jianlin Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene |
| title | Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene |
| title_full | Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene |
| title_fullStr | Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene |
| title_full_unstemmed | Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene |
| title_short | Mitochondrial DNA origin of indigenous Malagasy chicken: implication for a functional polymorphism at the Mx gene |
| title_sort | mitochondrial dna origin of indigenous malagasy chicken implication for a functional polymorphism at the mx gene |
| topic | chickens madagascar |
| url | https://hdl.handle.net/10568/1882 |
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