SPDC-HG: an accelerator of genomic hybrid breeding in maize
Integrating multiple modern breeding techniques in maize has always been challenging. This study aimed to address this issue by applying a flexible sparse partial diallel cross design composed of 945 maize hybrids derived from 266 inbred lines across different heterotic groups. The research integrat...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
John Wiley & Sons
2025
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| Acceso en línea: | https://hdl.handle.net/10568/179270 |
| _version_ | 1855519822764310528 |
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| author | Zhang, Zhenliang Wang, Xin Zhang, Yuxiang Zhou, Kai Yu, Guangning Yang, Wenyan Li, Furong Guan, Xiusheng Zhang, Xuecai Yang, Zefeng Xu, Chenwu Xu, Yang |
| author_browse | Guan, Xiusheng Li, Furong Wang, Xin Xu, Chenwu Xu, Yang Yang, Wenyan Yang, Zefeng Yu, Guangning Zhang, Xuecai Zhang, Yuxiang Zhang, Zhenliang Zhou, Kai |
| author_facet | Zhang, Zhenliang Wang, Xin Zhang, Yuxiang Zhou, Kai Yu, Guangning Yang, Wenyan Li, Furong Guan, Xiusheng Zhang, Xuecai Yang, Zefeng Xu, Chenwu Xu, Yang |
| author_sort | Zhang, Zhenliang |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Integrating multiple modern breeding techniques in maize has always been challenging. This study aimed to address this issue by applying a flexible sparse partial diallel cross design composed of 945 maize hybrids derived from 266 inbred lines across different heterotic groups. The research integrated genome-wide association studies, genomic selection and genomic evaluation of parental inbred lines to accelerate the breeding process for developing single-cross hybrids. Significant associations were identified for 7-25 stable single nucleotide polymorphisms (SNPs) associated with the general combining abilities (GCAs) of nine yield-related traits. Using the maizeGDB and NCBI databases, 264 candidate genes were screened and functionally annotated based on significant SNPs detected by at least three statistical methods. The marker set developed from these GCA SNPs significantly improved the prediction accuracy of hybrids across all traits. The GCA estimates of the inbred lines involved in the top 100 and bottom 100 hybrids consistently ranked at the top and bottom, thereby confirming the accuracy of the predictions. Furthermore, the top 100 crosses selected using BayesB, GBLUP and LASSO showed a 105.4-108.6% increase in average ear weight compared to the bottom 100 crosses in field validation, demonstrating strong selection gains. Notably, amongst the top 100 hybrids, A017/A037 and A037/A169, each containing six superior genotypes were registered as Suyu 161 and Tongyu 1701, respectively, by the National Crop Variety Approval Committee in China. These results highlight the effectiveness of genomic selection and provide valuable insights for advancing genomic hybrid breeding in maize. |
| format | Journal Article |
| id | CGSpace179270 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | John Wiley & Sons |
| publisherStr | John Wiley & Sons |
| record_format | dspace |
| spelling | CGSpace1792702025-12-24T02:04:13Z SPDC-HG: an accelerator of genomic hybrid breeding in maize Zhang, Zhenliang Wang, Xin Zhang, Yuxiang Zhou, Kai Yu, Guangning Yang, Wenyan Li, Furong Guan, Xiusheng Zhang, Xuecai Yang, Zefeng Xu, Chenwu Xu, Yang maize cross-breeding combining ability marker-assisted selection hybrids Integrating multiple modern breeding techniques in maize has always been challenging. This study aimed to address this issue by applying a flexible sparse partial diallel cross design composed of 945 maize hybrids derived from 266 inbred lines across different heterotic groups. The research integrated genome-wide association studies, genomic selection and genomic evaluation of parental inbred lines to accelerate the breeding process for developing single-cross hybrids. Significant associations were identified for 7-25 stable single nucleotide polymorphisms (SNPs) associated with the general combining abilities (GCAs) of nine yield-related traits. Using the maizeGDB and NCBI databases, 264 candidate genes were screened and functionally annotated based on significant SNPs detected by at least three statistical methods. The marker set developed from these GCA SNPs significantly improved the prediction accuracy of hybrids across all traits. The GCA estimates of the inbred lines involved in the top 100 and bottom 100 hybrids consistently ranked at the top and bottom, thereby confirming the accuracy of the predictions. Furthermore, the top 100 crosses selected using BayesB, GBLUP and LASSO showed a 105.4-108.6% increase in average ear weight compared to the bottom 100 crosses in field validation, demonstrating strong selection gains. Notably, amongst the top 100 hybrids, A017/A037 and A037/A169, each containing six superior genotypes were registered as Suyu 161 and Tongyu 1701, respectively, by the National Crop Variety Approval Committee in China. These results highlight the effectiveness of genomic selection and provide valuable insights for advancing genomic hybrid breeding in maize. 2025-05 2025-12-23T21:05:12Z 2025-12-23T21:05:12Z Journal Article https://hdl.handle.net/10568/179270 en Open Access application/pdf John Wiley & Sons Zhang, Z., Wang, X., Zhang, Y., Zhou, K., Yu, G., Yang, W., Li, F., Guan, X., Zhang, X., Yang, Z., Xu, C., & Xu, Y. (2025). SPDC‐HG: an accelerator of genomic hybrid breeding in maize. Plant Biotechnology Journal, 23(5), 1847-1861. https://doi.org/10.1111/pbi.70011 |
| spellingShingle | maize cross-breeding combining ability marker-assisted selection hybrids Zhang, Zhenliang Wang, Xin Zhang, Yuxiang Zhou, Kai Yu, Guangning Yang, Wenyan Li, Furong Guan, Xiusheng Zhang, Xuecai Yang, Zefeng Xu, Chenwu Xu, Yang SPDC-HG: an accelerator of genomic hybrid breeding in maize |
| title | SPDC-HG: an accelerator of genomic hybrid breeding in maize |
| title_full | SPDC-HG: an accelerator of genomic hybrid breeding in maize |
| title_fullStr | SPDC-HG: an accelerator of genomic hybrid breeding in maize |
| title_full_unstemmed | SPDC-HG: an accelerator of genomic hybrid breeding in maize |
| title_short | SPDC-HG: an accelerator of genomic hybrid breeding in maize |
| title_sort | spdc hg an accelerator of genomic hybrid breeding in maize |
| topic | maize cross-breeding combining ability marker-assisted selection hybrids |
| url | https://hdl.handle.net/10568/179270 |
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