Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities

Rift Valley fever (RVF), a zoonotic mosquito-borne viral disease with erratic occurrence and complex epidemiology, results in substantial costs to veterinary and public health and national economies. Since 1985, RVF virus (RVFV) epidemiology has focused on epidemics triggered by flood-induced emerge...

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Main Authors: Rostal, M.K., Thompson, P.N., Anyamba, A., Bett, Bernard K., Cêtre-Sossah, C., Chevalier, V., Guarido, M., Karesh, W.B., Kemp, A., LaBeaud, A.D., Lubisi, A., Matthews, L., Msimang, V., Njenga, M.K., Ross, N., Tumusiime, D., Wilson, W.C., Weyer, J., Paweska, J.T., Swanepoel, R.
Format: Journal Article
Language:Inglés
Published: Elsevier 2025
Subjects:
Online Access:https://hdl.handle.net/10568/176385
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author Rostal, M.K.
Thompson, P.N.
Anyamba, A.
Bett, Bernard K.
Cêtre-Sossah, C.
Chevalier, V.
Guarido, M.
Karesh, W.B.
Kemp, A.
LaBeaud, A.D.
Lubisi, A.
Matthews, L.
Msimang, V.
Njenga, M.K.
Ross, N.
Tumusiime, D.
Wilson, W.C.
Weyer, J.
Paweska, J.T.
Swanepoel, R.
author_browse Anyamba, A.
Bett, Bernard K.
Chevalier, V.
Cêtre-Sossah, C.
Guarido, M.
Karesh, W.B.
Kemp, A.
LaBeaud, A.D.
Lubisi, A.
Matthews, L.
Msimang, V.
Njenga, M.K.
Paweska, J.T.
Ross, N.
Rostal, M.K.
Swanepoel, R.
Thompson, P.N.
Tumusiime, D.
Weyer, J.
Wilson, W.C.
author_facet Rostal, M.K.
Thompson, P.N.
Anyamba, A.
Bett, Bernard K.
Cêtre-Sossah, C.
Chevalier, V.
Guarido, M.
Karesh, W.B.
Kemp, A.
LaBeaud, A.D.
Lubisi, A.
Matthews, L.
Msimang, V.
Njenga, M.K.
Ross, N.
Tumusiime, D.
Wilson, W.C.
Weyer, J.
Paweska, J.T.
Swanepoel, R.
author_sort Rostal, M.K.
collection Repository of Agricultural Research Outputs (CGSpace)
description Rift Valley fever (RVF), a zoonotic mosquito-borne viral disease with erratic occurrence and complex epidemiology, results in substantial costs to veterinary and public health and national economies. Since 1985, RVF virus (RVFV) epidemiology has focused on epidemics triggered by flood-induced emergence of transovarially infected mosquitoes, following an interepidemic period during which RVFV persists primarily in floodwater <i>Aedes</i> spp. mosquito eggs, with potential for low-level interepidemic circulation. In this Personal View, we challenge this classic framework of RVFV epidemiology, presenting instead a spectrum of RVFV dynamics ranging from epidemic to hyperendemic. We present the case for RVFV being maintained in a variable reservoir system of livestock, wildlife, and mosquitoes, with or without transovarial transmission. We highlight that sufficient evidence supports a shift in the paradigm of RVF epidemiology to embrace a more nuanced understanding of the spectrum of RVFV dynamics and call for more research into understanding the drivers of RVFV dynamics in hyperendemic areas.
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spelling CGSpace1763852025-12-08T10:11:39Z Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities Rostal, M.K. Thompson, P.N. Anyamba, A. Bett, Bernard K. Cêtre-Sossah, C. Chevalier, V. Guarido, M. Karesh, W.B. Kemp, A. LaBeaud, A.D. Lubisi, A. Matthews, L. Msimang, V. Njenga, M.K. Ross, N. Tumusiime, D. Wilson, W.C. Weyer, J. Paweska, J.T. Swanepoel, R. epidemiology research rift valley fever Rift Valley fever (RVF), a zoonotic mosquito-borne viral disease with erratic occurrence and complex epidemiology, results in substantial costs to veterinary and public health and national economies. Since 1985, RVF virus (RVFV) epidemiology has focused on epidemics triggered by flood-induced emergence of transovarially infected mosquitoes, following an interepidemic period during which RVFV persists primarily in floodwater <i>Aedes</i> spp. mosquito eggs, with potential for low-level interepidemic circulation. In this Personal View, we challenge this classic framework of RVFV epidemiology, presenting instead a spectrum of RVFV dynamics ranging from epidemic to hyperendemic. We present the case for RVFV being maintained in a variable reservoir system of livestock, wildlife, and mosquitoes, with or without transovarial transmission. We highlight that sufficient evidence supports a shift in the paradigm of RVF epidemiology to embrace a more nuanced understanding of the spectrum of RVFV dynamics and call for more research into understanding the drivers of RVFV dynamics in hyperendemic areas. 2025-09 2025-09-08T12:52:07Z 2025-09-08T12:52:07Z Journal Article https://hdl.handle.net/10568/176385 en Open Access Elsevier Rostal, M.K., Thompson, P.N., Anyamba, A., Bett, B., Cêtre-Sossah, C., Chevalier, V., Guarido, M., Karesh, W.B., Kemp, A., LaBeaud, A.D., Lubisi, A., Matthews, L., Msimang, V., Njenga, M.K., Ross, N., Tumusiime, D., Wilson, W.C., Weyer, J., Paweska, J.T. and Swanepoel, R. 2025. Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities. Lancet Planetary Health 9(9): 101299.
spellingShingle epidemiology
research
rift valley fever
Rostal, M.K.
Thompson, P.N.
Anyamba, A.
Bett, Bernard K.
Cêtre-Sossah, C.
Chevalier, V.
Guarido, M.
Karesh, W.B.
Kemp, A.
LaBeaud, A.D.
Lubisi, A.
Matthews, L.
Msimang, V.
Njenga, M.K.
Ross, N.
Tumusiime, D.
Wilson, W.C.
Weyer, J.
Paweska, J.T.
Swanepoel, R.
Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities
title Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities
title_full Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities
title_fullStr Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities
title_full_unstemmed Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities
title_short Rift Valley fever epidemiology: shifting the paradigm and rethinking research priorities
title_sort rift valley fever epidemiology shifting the paradigm and rethinking research priorities
topic epidemiology
research
rift valley fever
url https://hdl.handle.net/10568/176385
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