Genomic prediction of tocochromanols in exotic-derived maize

Tocochromanols (vitamin E) are an essential part of the human diet. Plant products, including maize (Zea mays L.) grain, are the major dietary source of tocochromanols; therefore, breeding maize with higher vitamin content (biofortification) could improve human nutrition. Incorporating exotic germpl...

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Autores principales: Tibbs-Cortes, Laura E., Guo, Tingting, Li, Xianran, Tanaka, Ryokei, Vanous, Adam E., Peters, David, Gardner, Candice, Magallanes-Lundback, Maria, Deason, Nicholas T., DellaPenna, Dean, Gore, Michael A., Yu, Jianming
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2023
Materias:
Acceso en línea:https://hdl.handle.net/10568/175678
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author Tibbs-Cortes, Laura E.
Guo, Tingting
Li, Xianran
Tanaka, Ryokei
Vanous, Adam E.
Peters, David
Gardner, Candice
Magallanes-Lundback, Maria
Deason, Nicholas T.
DellaPenna, Dean
Gore, Michael A.
Yu, Jianming
author_browse Deason, Nicholas T.
DellaPenna, Dean
Gardner, Candice
Gore, Michael A.
Guo, Tingting
Li, Xianran
Magallanes-Lundback, Maria
Peters, David
Tanaka, Ryokei
Tibbs-Cortes, Laura E.
Vanous, Adam E.
Yu, Jianming
author_facet Tibbs-Cortes, Laura E.
Guo, Tingting
Li, Xianran
Tanaka, Ryokei
Vanous, Adam E.
Peters, David
Gardner, Candice
Magallanes-Lundback, Maria
Deason, Nicholas T.
DellaPenna, Dean
Gore, Michael A.
Yu, Jianming
author_sort Tibbs-Cortes, Laura E.
collection Repository of Agricultural Research Outputs (CGSpace)
description Tocochromanols (vitamin E) are an essential part of the human diet. Plant products, including maize (Zea mays L.) grain, are the major dietary source of tocochromanols; therefore, breeding maize with higher vitamin content (biofortification) could improve human nutrition. Incorporating exotic germplasm in maize breeding for trait improvement including biofortification is a promising approach and an important research topic. However, information about genomic prediction of exotic-derived lines using available training data from adapted germplasm is limited. In this study, genomic prediction was systematically investigated for nine tocochromanol traits within both an adapted (Ames Diversity Panel [AP]) and an exotic-derived (Backcrossed Germplasm Enhancement of Maize [BGEM]) maize population. Although prediction accuracies up to 0.79 were achieved using genomic best linear unbiased prediction (gBLUP) when predicting within each population, genomic prediction of BGEM based on an AP training set resulted in low prediction accuracies. Optimal training population (OTP) design methods fast and unique representative subset selection (FURS), maximization of connectedness and diversity (MaxCD), and partitioning around medoids (PAM) were adapted for inbreds and, along with the methods mean coefficient of determination (CDmean) and mean prediction error variance (PEVmean), often improved prediction accuracies compared with random training sets of the same size. When applied to the combined population, OTP designs enabled successful prediction of the rest of the exotic-derived population. Our findings highlight the importance of leveraging genotype data in training set design to efficiently incorporate new exotic germplasm into a plant breeding program.
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spelling CGSpace1756782025-07-17T17:01:51Z Genomic prediction of tocochromanols in exotic-derived maize Tibbs-Cortes, Laura E. Guo, Tingting Li, Xianran Tanaka, Ryokei Vanous, Adam E. Peters, David Gardner, Candice Magallanes-Lundback, Maria Deason, Nicholas T. DellaPenna, Dean Gore, Michael A. Yu, Jianming vitamin E maize nutrition germplasm biofortification fat soluble vitamins Tocochromanols (vitamin E) are an essential part of the human diet. Plant products, including maize (Zea mays L.) grain, are the major dietary source of tocochromanols; therefore, breeding maize with higher vitamin content (biofortification) could improve human nutrition. Incorporating exotic germplasm in maize breeding for trait improvement including biofortification is a promising approach and an important research topic. However, information about genomic prediction of exotic-derived lines using available training data from adapted germplasm is limited. In this study, genomic prediction was systematically investigated for nine tocochromanol traits within both an adapted (Ames Diversity Panel [AP]) and an exotic-derived (Backcrossed Germplasm Enhancement of Maize [BGEM]) maize population. Although prediction accuracies up to 0.79 were achieved using genomic best linear unbiased prediction (gBLUP) when predicting within each population, genomic prediction of BGEM based on an AP training set resulted in low prediction accuracies. Optimal training population (OTP) design methods fast and unique representative subset selection (FURS), maximization of connectedness and diversity (MaxCD), and partitioning around medoids (PAM) were adapted for inbreds and, along with the methods mean coefficient of determination (CDmean) and mean prediction error variance (PEVmean), often improved prediction accuracies compared with random training sets of the same size. When applied to the combined population, OTP designs enabled successful prediction of the rest of the exotic-derived population. Our findings highlight the importance of leveraging genotype data in training set design to efficiently incorporate new exotic germplasm into a plant breeding program. 2023-12 2025-07-17T17:01:50Z 2025-07-17T17:01:50Z Journal Article https://hdl.handle.net/10568/175678 en Open Access Wiley Tibbs-Cortes, Laura E.; Guo, Tingting; Li, Xianran; Tanaka, Ryokei; Vanous, Adam E.; Peters, David; et al. 2023. Genomic prediction of tocochromanols in exotic-derived maize. Plant Genome 16(4): e20286. https://doi.org/10.1002/tpg2.20286
spellingShingle vitamin E
maize
nutrition
germplasm
biofortification
fat soluble vitamins
Tibbs-Cortes, Laura E.
Guo, Tingting
Li, Xianran
Tanaka, Ryokei
Vanous, Adam E.
Peters, David
Gardner, Candice
Magallanes-Lundback, Maria
Deason, Nicholas T.
DellaPenna, Dean
Gore, Michael A.
Yu, Jianming
Genomic prediction of tocochromanols in exotic-derived maize
title Genomic prediction of tocochromanols in exotic-derived maize
title_full Genomic prediction of tocochromanols in exotic-derived maize
title_fullStr Genomic prediction of tocochromanols in exotic-derived maize
title_full_unstemmed Genomic prediction of tocochromanols in exotic-derived maize
title_short Genomic prediction of tocochromanols in exotic-derived maize
title_sort genomic prediction of tocochromanols in exotic derived maize
topic vitamin E
maize
nutrition
germplasm
biofortification
fat soluble vitamins
url https://hdl.handle.net/10568/175678
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