A chromosomal level genome assembly of Nguni sheep, Ovis aries
Nguni sheep (<i>Ovis aries</i>) are indigenous to the Southern Africa region and common within the smallholder and poor resources farming systems. They are well adapted to different agroecological regions. However, limited genomic resources such as high-quality reference genomes have hindered our un...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Nature Research
2025
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| Acceso en línea: | https://hdl.handle.net/10568/175624 |
| _version_ | 1855517296970170368 |
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| author | Nesengani, L.T. Tshilate, T. Mdyogolo, S. Smith, R. Masebe, T. Raphulu, T. Moila, A. Sharaf, A. Muzemil, S. Houaga, I. Muigai, A. Djikeng, Appolinaire Kuja, J. Katee, Sally Osuji, J.O. Mungloo-Dilmohamud, Z. Botes, M. Mbizeni, S. Jarvis, E. Ebenezer, T.E. Ntanganedzeni, M. |
| author_browse | Botes, M. Djikeng, Appolinaire Ebenezer, T.E. Houaga, I. Jarvis, E. Katee, Sally Kuja, J. Masebe, T. Mbizeni, S. Mdyogolo, S. Moila, A. Muigai, A. Mungloo-Dilmohamud, Z. Muzemil, S. Nesengani, L.T. Ntanganedzeni, M. Osuji, J.O. Raphulu, T. Sharaf, A. Smith, R. Tshilate, T. |
| author_facet | Nesengani, L.T. Tshilate, T. Mdyogolo, S. Smith, R. Masebe, T. Raphulu, T. Moila, A. Sharaf, A. Muzemil, S. Houaga, I. Muigai, A. Djikeng, Appolinaire Kuja, J. Katee, Sally Osuji, J.O. Mungloo-Dilmohamud, Z. Botes, M. Mbizeni, S. Jarvis, E. Ebenezer, T.E. Ntanganedzeni, M. |
| author_sort | Nesengani, L.T. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Nguni sheep (<i>Ovis aries</i>) are indigenous to the Southern Africa region and common within the smallholder and poor resources farming systems. They are well adapted to different agroecological regions. However, limited genomic resources such as high-quality reference genomes have hindered our understanding of its adaptation and establishment of an effective breeding program. To address this, we assembled a chromosomal-level genome of Nguni sheep using a combination of PacBio HiFi reads and Omni-C reads. The genome size was estimated to be 2.9 Gb with a contig/scaffold N50 74 Mb and 99.6 Mb and a genome completeness of 96.1%, as estimated by the Benchmarking Universal Single-Copy Orthologs (BUSCO) program. The final genome encompassed a total of 25,926 protein-coding genes. The findings of this study provide a valuable genomic resource for understanding the adaptability of the Nguni sheep and the establishment of effective breeding programs. |
| format | Journal Article |
| id | CGSpace175624 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Nature Research |
| publisherStr | Nature Research |
| record_format | dspace |
| spelling | CGSpace1756242025-12-08T10:06:44Z A chromosomal level genome assembly of Nguni sheep, Ovis aries Nesengani, L.T. Tshilate, T. Mdyogolo, S. Smith, R. Masebe, T. Raphulu, T. Moila, A. Sharaf, A. Muzemil, S. Houaga, I. Muigai, A. Djikeng, Appolinaire Kuja, J. Katee, Sally Osuji, J.O. Mungloo-Dilmohamud, Z. Botes, M. Mbizeni, S. Jarvis, E. Ebenezer, T.E. Ntanganedzeni, M. genomics sheep small ruminants Nguni sheep (<i>Ovis aries</i>) are indigenous to the Southern Africa region and common within the smallholder and poor resources farming systems. They are well adapted to different agroecological regions. However, limited genomic resources such as high-quality reference genomes have hindered our understanding of its adaptation and establishment of an effective breeding program. To address this, we assembled a chromosomal-level genome of Nguni sheep using a combination of PacBio HiFi reads and Omni-C reads. The genome size was estimated to be 2.9 Gb with a contig/scaffold N50 74 Mb and 99.6 Mb and a genome completeness of 96.1%, as estimated by the Benchmarking Universal Single-Copy Orthologs (BUSCO) program. The final genome encompassed a total of 25,926 protein-coding genes. The findings of this study provide a valuable genomic resource for understanding the adaptability of the Nguni sheep and the establishment of effective breeding programs. 2025-07-10 2025-07-14T04:02:17Z 2025-07-14T04:02:17Z Journal Article https://hdl.handle.net/10568/175624 en Open Access Nature Research Nesengani, L.T., Tshilate, T., Mdyogolo, S., Smith, R., Masebe, T., Raphulu, T., Moila, A., Sharaf, A., Muzemil, S., Houaga, I., Muigai, A., Djikeng, A., Kuja, J., Katee, S., Osuji, J.O., Mungloo-Dilmohamud, Z., Botes, M., Mbizeni, S., Jarvis, E., Ebenezer, T.E. and Ntanganedzeni, M. 2025. A chromosomal level genome assembly of Nguni sheep, <i>Ovis aries</i>. Scientific Data 12: 1193. |
| spellingShingle | genomics sheep small ruminants Nesengani, L.T. Tshilate, T. Mdyogolo, S. Smith, R. Masebe, T. Raphulu, T. Moila, A. Sharaf, A. Muzemil, S. Houaga, I. Muigai, A. Djikeng, Appolinaire Kuja, J. Katee, Sally Osuji, J.O. Mungloo-Dilmohamud, Z. Botes, M. Mbizeni, S. Jarvis, E. Ebenezer, T.E. Ntanganedzeni, M. A chromosomal level genome assembly of Nguni sheep, Ovis aries |
| title | A chromosomal level genome assembly of Nguni sheep, Ovis aries |
| title_full | A chromosomal level genome assembly of Nguni sheep, Ovis aries |
| title_fullStr | A chromosomal level genome assembly of Nguni sheep, Ovis aries |
| title_full_unstemmed | A chromosomal level genome assembly of Nguni sheep, Ovis aries |
| title_short | A chromosomal level genome assembly of Nguni sheep, Ovis aries |
| title_sort | chromosomal level genome assembly of nguni sheep ovis aries |
| topic | genomics sheep small ruminants |
| url | https://hdl.handle.net/10568/175624 |
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