Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm
Fusarium head blight (FHB) is an important disease throughout the world due to its strong association with yield reduction, quality deterioration, and mycotoxin contamination in wheat. The use of FHB-resistant genotypes in wheat production can significantly reduce damage. The current study screened...
| Autores principales: | , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2025
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/175606 |
| _version_ | 1855531173553373184 |
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| author | Mandal, Rupsanatan Xinyao He Singh, Gyanendra Pratap Kabir, Muhammad Rezaul Joshi, Arun Kumar Pawan Kumar Singh |
| author_browse | Joshi, Arun Kumar Kabir, Muhammad Rezaul Mandal, Rupsanatan Pawan Kumar Singh Singh, Gyanendra Pratap Xinyao He |
| author_facet | Mandal, Rupsanatan Xinyao He Singh, Gyanendra Pratap Kabir, Muhammad Rezaul Joshi, Arun Kumar Pawan Kumar Singh |
| author_sort | Mandal, Rupsanatan |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Fusarium head blight (FHB) is an important disease throughout the world due to its strong association with yield reduction, quality deterioration, and mycotoxin contamination in wheat. The use of FHB-resistant genotypes in wheat production can significantly reduce damage. The current study screened a panel of bread wheat from CIMMYT and South Asian countries for FHB resistance to identify promising genotypes useful for wheat breeding and to map the associated genomic regions and linked molecular markers through a genome-wide association study (GWAS). Spray-inoculated field experiments were conducted at CIMMYT, Mexico, over three years, and a wide range of phenotypic variations was observed. Four lines, CIM-39, CIM-29, CIM-9, and CIM-3, exhibited consistent resistance across experiments, with FHB indices ranging from 6.5 to 8.1. Genotyping was conducted using the Illumina Infinium 15 K Bead Chip, and 11,184 high-quality SNP markers were obtained and used for GWAS. Nineteen significant marker-trait associations (MTAs) were detected, among which MTAs at Ra_c58315_265 on 1A and Tdurum_contig102328_129 and Ku_c20136_198 on 7B showed reproducible results, with phenotypic effects on FHB resistance of 6.05%, 3.54%, and 3.92%, respectively. Several genes associated with disease resistance were found near the significant SNPs. The identified resistant genotypes and markers may be useful in future marker-assisted breeding in wheat. |
| format | Journal Article |
| id | CGSpace175606 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1756062025-07-11T01:07:52Z Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm Mandal, Rupsanatan Xinyao He Singh, Gyanendra Pratap Kabir, Muhammad Rezaul Joshi, Arun Kumar Pawan Kumar Singh fusarium genome-wide association studies wheat single nucleotide polymorphisms Fusarium head blight (FHB) is an important disease throughout the world due to its strong association with yield reduction, quality deterioration, and mycotoxin contamination in wheat. The use of FHB-resistant genotypes in wheat production can significantly reduce damage. The current study screened a panel of bread wheat from CIMMYT and South Asian countries for FHB resistance to identify promising genotypes useful for wheat breeding and to map the associated genomic regions and linked molecular markers through a genome-wide association study (GWAS). Spray-inoculated field experiments were conducted at CIMMYT, Mexico, over three years, and a wide range of phenotypic variations was observed. Four lines, CIM-39, CIM-29, CIM-9, and CIM-3, exhibited consistent resistance across experiments, with FHB indices ranging from 6.5 to 8.1. Genotyping was conducted using the Illumina Infinium 15 K Bead Chip, and 11,184 high-quality SNP markers were obtained and used for GWAS. Nineteen significant marker-trait associations (MTAs) were detected, among which MTAs at Ra_c58315_265 on 1A and Tdurum_contig102328_129 and Ku_c20136_198 on 7B showed reproducible results, with phenotypic effects on FHB resistance of 6.05%, 3.54%, and 3.92%, respectively. Several genes associated with disease resistance were found near the significant SNPs. The identified resistant genotypes and markers may be useful in future marker-assisted breeding in wheat. 2025-05-16 2025-07-10T22:16:17Z 2025-07-10T22:16:17Z Journal Article https://hdl.handle.net/10568/175606 en Open Access application/pdf MDPI Mandal, R., He, X., Singh, G. P., Kabir, M. R., Joshi, A. K., & Singh, P. K. (2025). Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm. Pathogens, 14(5), 490. https://doi.org/10.3390/pathogens14050490 |
| spellingShingle | fusarium genome-wide association studies wheat single nucleotide polymorphisms Mandal, Rupsanatan Xinyao He Singh, Gyanendra Pratap Kabir, Muhammad Rezaul Joshi, Arun Kumar Pawan Kumar Singh Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm |
| title | Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm |
| title_full | Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm |
| title_fullStr | Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm |
| title_full_unstemmed | Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm |
| title_short | Evaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm |
| title_sort | evaluation of fusarium head blight resistance through a genome wide association study in cimmyt and south asian wheat germplasm |
| topic | fusarium genome-wide association studies wheat single nucleotide polymorphisms |
| url | https://hdl.handle.net/10568/175606 |
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