Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)

Common bean (Phaseolus vulgaris L.) is one of the most abundantly consumed legume crops as foods worldwide. In many African countries, this crop is an important staple food because of its rich nutrients. The Great Lakes region of Central Africa, which includes Rwanda, the nation with the highest per...

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Main Authors: Mukamuhirwa, Floride, Shirasawa, Kenta, Naito, Ken, Rurangwa, Edouard, Ndayizeye, Viateur, Nyombayire, Alphonse, Muhire, Jean Pierre, Govindaraj, Mahalingam, Ohtake, Norikuni, Okazaki, Keiichi, Okada, Moeko, Fukai, Eigo
Format: Journal Article
Language:Inglés
Published: Japanese Society of Breeding 2025
Subjects:
Online Access:https://hdl.handle.net/10568/175516
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author Mukamuhirwa, Floride
Shirasawa, Kenta
Naito, Ken
Rurangwa, Edouard
Ndayizeye, Viateur
Nyombayire, Alphonse
Muhire, Jean Pierre
Govindaraj, Mahalingam
Ohtake, Norikuni
Okazaki, Keiichi
Okada, Moeko
Fukai, Eigo
author_browse Fukai, Eigo
Govindaraj, Mahalingam
Muhire, Jean Pierre
Mukamuhirwa, Floride
Naito, Ken
Ndayizeye, Viateur
Nyombayire, Alphonse
Ohtake, Norikuni
Okada, Moeko
Okazaki, Keiichi
Rurangwa, Edouard
Shirasawa, Kenta
author_facet Mukamuhirwa, Floride
Shirasawa, Kenta
Naito, Ken
Rurangwa, Edouard
Ndayizeye, Viateur
Nyombayire, Alphonse
Muhire, Jean Pierre
Govindaraj, Mahalingam
Ohtake, Norikuni
Okazaki, Keiichi
Okada, Moeko
Fukai, Eigo
author_sort Mukamuhirwa, Floride
collection Repository of Agricultural Research Outputs (CGSpace)
description Common bean (Phaseolus vulgaris L.) is one of the most abundantly consumed legume crops as foods worldwide. In many African countries, this crop is an important staple food because of its rich nutrients. The Great Lakes region of Central Africa, which includes Rwanda, the nation with the highest per capita consumption of common beans worldwide, is known to be a center of common bean diversity in Africa. Increasing the amount of iron and zinc in common bean for biofortification has been a key breeding goal in Rwanda and other countries. In this study, using 192 accessions, including local landraces from Rwanda, breeding materials, released varieties, and others, we performed genome wide association studies (GWAS) to determine the loci governing those traits in addition to other agronomic traits. We identified a locus that was strongly associated with seed zinc concentration and candidate genes. The information might be a great help for marker-assisted breeding of this trait in common bean.
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spelling CGSpace1755162025-11-26T15:26:49Z Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS) Mukamuhirwa, Floride Shirasawa, Kenta Naito, Ken Rurangwa, Edouard Ndayizeye, Viateur Nyombayire, Alphonse Muhire, Jean Pierre Govindaraj, Mahalingam Ohtake, Norikuni Okazaki, Keiichi Okada, Moeko Fukai, Eigo biofortification common beans genomes iron zinc Common bean (Phaseolus vulgaris L.) is one of the most abundantly consumed legume crops as foods worldwide. In many African countries, this crop is an important staple food because of its rich nutrients. The Great Lakes region of Central Africa, which includes Rwanda, the nation with the highest per capita consumption of common beans worldwide, is known to be a center of common bean diversity in Africa. Increasing the amount of iron and zinc in common bean for biofortification has been a key breeding goal in Rwanda and other countries. In this study, using 192 accessions, including local landraces from Rwanda, breeding materials, released varieties, and others, we performed genome wide association studies (GWAS) to determine the loci governing those traits in addition to other agronomic traits. We identified a locus that was strongly associated with seed zinc concentration and candidate genes. The information might be a great help for marker-assisted breeding of this trait in common bean. 2025-07 2025-07-07T17:03:36Z 2025-07-07T17:03:36Z Journal Article https://hdl.handle.net/10568/175516 en Open Access Japanese Society of Breeding Mukamuhirwa, Floride; Shirasawa, Kenta; Naito, Ken; Rurangwa, Edouard; Ndayizeye, Viateur; Nyombayire, Alphonse; et al. 2025. Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS). Breeding Science 75(3): 187-199. https://doi.org/10.1270/jsbbs.24087
spellingShingle biofortification
common beans
genomes
iron
zinc
Mukamuhirwa, Floride
Shirasawa, Kenta
Naito, Ken
Rurangwa, Edouard
Ndayizeye, Viateur
Nyombayire, Alphonse
Muhire, Jean Pierre
Govindaraj, Mahalingam
Ohtake, Norikuni
Okazaki, Keiichi
Okada, Moeko
Fukai, Eigo
Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)
title Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)
title_full Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)
title_fullStr Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)
title_full_unstemmed Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)
title_short Genetic control of seed iron and zinc concentration in Rwandan common bean population revealed by the Genome Wide Association Study (GWAS)
title_sort genetic control of seed iron and zinc concentration in rwandan common bean population revealed by the genome wide association study gwas
topic biofortification
common beans
genomes
iron
zinc
url https://hdl.handle.net/10568/175516
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