Nontargeted metabolomics: PTFI Platform
The PTFI Nontargeted Metabolomics platform supports the characterization of the small molecule composition in food. This method uses solid phase extraction (SPE) to isolate small molecules for analysis by reverse phased liquid chromatography-high resolution mass spectrometry (LC-HRMS). The PTFI N...
| Autores principales: | , , , |
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| Formato: | Brief |
| Lenguaje: | Inglés |
| Publicado: |
2025
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/174494 |
| _version_ | 1855519024372252672 |
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| author | Watkins, Steve Odenkirk, Melanie T Prenni, Jessica Brinkley, Sarah |
| author_browse | Brinkley, Sarah Odenkirk, Melanie T Prenni, Jessica Watkins, Steve |
| author_facet | Watkins, Steve Odenkirk, Melanie T Prenni, Jessica Brinkley, Sarah |
| author_sort | Watkins, Steve |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The PTFI Nontargeted Metabolomics platform supports the characterization of the small molecule composition in food. This method uses solid phase extraction (SPE) to isolate small molecules for analysis by reverse phased liquid chromatography-high resolution mass spectrometry (LC-HRMS).
The PTFI Nontargeted Metabolomics platform is adapted from existing protocols used by researchers. What sets the PTFI method apart is the focus on standardization and the incorporation of a unique internal retention standard reagent which is a mixture of 33 compounds nonendogenous to food. When researchers around the world employ the same standardized protocol and utilize the same internal standard reagent the resulting data can be harmonized and becomes comparable – allowing us to build a scalable data resource. |
| format | Brief |
| id | CGSpace174494 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| record_format | dspace |
| spelling | CGSpace1744942025-11-05T11:12:22Z Nontargeted metabolomics: PTFI Platform Watkins, Steve Odenkirk, Melanie T Prenni, Jessica Brinkley, Sarah nutrition metabolomics food composition The PTFI Nontargeted Metabolomics platform supports the characterization of the small molecule composition in food. This method uses solid phase extraction (SPE) to isolate small molecules for analysis by reverse phased liquid chromatography-high resolution mass spectrometry (LC-HRMS). The PTFI Nontargeted Metabolomics platform is adapted from existing protocols used by researchers. What sets the PTFI method apart is the focus on standardization and the incorporation of a unique internal retention standard reagent which is a mixture of 33 compounds nonendogenous to food. When researchers around the world employ the same standardized protocol and utilize the same internal standard reagent the resulting data can be harmonized and becomes comparable – allowing us to build a scalable data resource. 2025-05 2025-05-09T07:21:00Z 2025-05-09T07:21:00Z Brief https://hdl.handle.net/10568/174494 en Open Access application/pdf Watkins, S.; Odenkirk, M.T.; Prenni, J.; Brinkley, S. (2025) Nontargeted metabolomics: PTFI Platform. 3 p. |
| spellingShingle | nutrition metabolomics food composition Watkins, Steve Odenkirk, Melanie T Prenni, Jessica Brinkley, Sarah Nontargeted metabolomics: PTFI Platform |
| title | Nontargeted metabolomics: PTFI Platform |
| title_full | Nontargeted metabolomics: PTFI Platform |
| title_fullStr | Nontargeted metabolomics: PTFI Platform |
| title_full_unstemmed | Nontargeted metabolomics: PTFI Platform |
| title_short | Nontargeted metabolomics: PTFI Platform |
| title_sort | nontargeted metabolomics ptfi platform |
| topic | nutrition metabolomics food composition |
| url | https://hdl.handle.net/10568/174494 |
| work_keys_str_mv | AT watkinssteve nontargetedmetabolomicsptfiplatform AT odenkirkmelaniet nontargetedmetabolomicsptfiplatform AT prennijessica nontargetedmetabolomicsptfiplatform AT brinkleysarah nontargetedmetabolomicsptfiplatform |