Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia

Despite the potential for improving iron status and child growth in low- and middle-income settings, concerns on the safety of high iron dosages of Micronutrient Powders (MNP currently limit their applicability in programs. We examined the effectiveness and risks of an integrated complementary feedi...

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Autores principales: Samuel, Aregash, Brouwer, Inge D., Feskens, Edith J., Adish, Abdulaziz, Kebede, Amha
Formato: Journal Article
Lenguaje:Inglés
Publicado: MDPI 2018
Materias:
Acceso en línea:https://hdl.handle.net/10568/171210
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author Samuel, Aregash
Brouwer, Inge D.
Feskens, Edith J.
Adish, Abdulaziz
Kebede, Amha
author_browse Adish, Abdulaziz
Brouwer, Inge D.
Feskens, Edith J.
Kebede, Amha
Samuel, Aregash
author_facet Samuel, Aregash
Brouwer, Inge D.
Feskens, Edith J.
Adish, Abdulaziz
Kebede, Amha
author_sort Samuel, Aregash
collection Repository of Agricultural Research Outputs (CGSpace)
description Despite the potential for improving iron status and child growth in low- and middle-income settings, concerns on the safety of high iron dosages of Micronutrient Powders (MNP currently limit their applicability in programs. We examined the effectiveness and risks of an integrated complementary feeding program with low iron dose (6 mg/serving) MNP among 6–23-month-old Ethiopian children using a quasi-experimental study design comparing children from five intervention districts (n = 1172) to those from four matched non-intervention districts (n = 1137). Haemoglobin concentrations increased in intervention and decreased in non-intervention children (group-difference +3.17 g/L), but without improvement in iron stores. Intervention children were 2.31 times more likely to have diarrhoea and 2.08 times more likely to have common cold and flu, but these differences decreased towards the end of the intervention. At end line, intervention children had higher mean Height-for-Age Zscore (HAZ) and a 51% reduced odds of being stunted compared to non-intervention children. MNP with low iron dose, when provided combined with other Infant and Young Child Feeding (IYCF) interventions, marginally improved haemoglobin status and resulted in a remarkable improvement in linear growth in 6–23-month-old children. These benefits likely outweigh the relatively small increase in the risk of diarrhoea.
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spelling CGSpace1712102025-02-19T14:31:38Z Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia Samuel, Aregash Brouwer, Inge D. Feskens, Edith J. Adish, Abdulaziz Kebede, Amha programmes iron trace elements morbidity growth children child nutrition complementary foods diarrhoea respiratory diseases influenzavirus quantitative analysis infant feeding child feeding Despite the potential for improving iron status and child growth in low- and middle-income settings, concerns on the safety of high iron dosages of Micronutrient Powders (MNP currently limit their applicability in programs. We examined the effectiveness and risks of an integrated complementary feeding program with low iron dose (6 mg/serving) MNP among 6–23-month-old Ethiopian children using a quasi-experimental study design comparing children from five intervention districts (n = 1172) to those from four matched non-intervention districts (n = 1137). Haemoglobin concentrations increased in intervention and decreased in non-intervention children (group-difference +3.17 g/L), but without improvement in iron stores. Intervention children were 2.31 times more likely to have diarrhoea and 2.08 times more likely to have common cold and flu, but these differences decreased towards the end of the intervention. At end line, intervention children had higher mean Height-for-Age Zscore (HAZ) and a 51% reduced odds of being stunted compared to non-intervention children. MNP with low iron dose, when provided combined with other Infant and Young Child Feeding (IYCF) interventions, marginally improved haemoglobin status and resulted in a remarkable improvement in linear growth in 6–23-month-old children. These benefits likely outweigh the relatively small increase in the risk of diarrhoea. 2018 2025-01-29T12:57:51Z 2025-01-29T12:57:51Z Journal Article https://hdl.handle.net/10568/171210 en Open Access MDPI Samuel, Aregash; Brouwer, Inge D.; Feskens, Edith J.; Adish, Abdulaziz; Kebede, Amha; et al. 2018. Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia. Nutrients 10(10): 1508. https://doi.org/10.3390/nu10101508
spellingShingle programmes
iron
trace elements
morbidity
growth
children
child nutrition
complementary foods
diarrhoea
respiratory diseases
influenzavirus
quantitative analysis
infant feeding
child feeding
Samuel, Aregash
Brouwer, Inge D.
Feskens, Edith J.
Adish, Abdulaziz
Kebede, Amha
Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia
title Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia
title_full Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia
title_fullStr Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia
title_full_unstemmed Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia
title_short Effectiveness of a program intervention with reduced-iron multiple micronutrient powders on iron status, morbidity and growth in young children in Ethiopia
title_sort effectiveness of a program intervention with reduced iron multiple micronutrient powders on iron status morbidity and growth in young children in ethiopia
topic programmes
iron
trace elements
morbidity
growth
children
child nutrition
complementary foods
diarrhoea
respiratory diseases
influenzavirus
quantitative analysis
infant feeding
child feeding
url https://hdl.handle.net/10568/171210
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