Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids
Biofortification of maize with provitamin A carotenoids is an emerging intervention for providing vitamin A to people where maize is a staple crop. Analyzing the effectiveness of biofortified maize adoption will be important in the coming years. We propose that serum carotenoid profiles will be idea...
| Autores principales: | , , |
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| Formato: | Resumen |
| Lenguaje: | Inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/171047 |
| _version_ | 1855515817318285312 |
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| author | Titcomb, Tyler J. Davis, Christopher R. Tanumihardjo, Sherry A. |
| author_browse | Davis, Christopher R. Tanumihardjo, Sherry A. Titcomb, Tyler J. |
| author_facet | Titcomb, Tyler J. Davis, Christopher R. Tanumihardjo, Sherry A. |
| author_sort | Titcomb, Tyler J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Biofortification of maize with provitamin A carotenoids is an emerging intervention for providing vitamin A to people where maize is a staple crop. Analyzing the effectiveness of biofortified maize adoption will be important in the coming years. We propose that serum carotenoid profiles will be ideal for this endeavor. The C30 HPLC column was developed specifically for carotenoid separations because the longer alkyl chains provide better separation of carotenoids and their respected isomers. Most types of maize that have been released also have enhanced concentrations of the xanthophyll carotenoids lutein and zeaxanthin. Due to the chemical similarity of lutein and zeaxanthin, the C30 column is ideal for analysis because it is capable of maintaining separation of these two non-provitamin A carotenoids. A potential drawback of the C30 column is longer analytical time specifically for lycopene. When monitoring study subject low carotenoid diets during a human maize feeding trial, we prop |
| format | Abstract |
| id | CGSpace171047 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | CGSpace1710472025-01-29T12:57:38Z Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids Titcomb, Tyler J. Davis, Christopher R. Tanumihardjo, Sherry A. nutrition bioavailability retinol maize carotenoids Biofortification of maize with provitamin A carotenoids is an emerging intervention for providing vitamin A to people where maize is a staple crop. Analyzing the effectiveness of biofortified maize adoption will be important in the coming years. We propose that serum carotenoid profiles will be ideal for this endeavor. The C30 HPLC column was developed specifically for carotenoid separations because the longer alkyl chains provide better separation of carotenoids and their respected isomers. Most types of maize that have been released also have enhanced concentrations of the xanthophyll carotenoids lutein and zeaxanthin. Due to the chemical similarity of lutein and zeaxanthin, the C30 column is ideal for analysis because it is capable of maintaining separation of these two non-provitamin A carotenoids. A potential drawback of the C30 column is longer analytical time specifically for lycopene. When monitoring study subject low carotenoid diets during a human maize feeding trial, we prop 2017 2025-01-29T12:57:38Z 2025-01-29T12:57:38Z Abstract https://hdl.handle.net/10568/171047 en Limited Access Titcomb, Tyler James; Davis, Christopher R.; and Tanumihardjo, Sherry A. 2017. Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids. FASEB 3 (Supplement1): 635.6: http://www.fasebj.org/content/31/1_Supplement/635.6.short |
| spellingShingle | nutrition bioavailability retinol maize carotenoids Titcomb, Tyler J. Davis, Christopher R. Tanumihardjo, Sherry A. Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids |
| title | Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids |
| title_full | Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids |
| title_fullStr | Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids |
| title_full_unstemmed | Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids |
| title_short | Application of a high-performance liquid chromatography method for the evaluation of non-provitamin A carotenoids |
| title_sort | application of a high performance liquid chromatography method for the evaluation of non provitamin a carotenoids |
| topic | nutrition bioavailability retinol maize carotenoids |
| url | https://hdl.handle.net/10568/171047 |
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