Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C

This work was performed to generate the data needed to set epidemiological cut-off values for minimal inhibitory concentrations (MICs) of 10 antimicrobial agents against Vibrio parahaemolyticus determined using standardised broth microdilution protocols. Eight laboratories performed broth microdilut...

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Autores principales: Smith, Peter, Joseph, Andrew, Baker-Austin, Craig, Kang, Nisha, Baron, Sandrine, Le Devendec, Laëtitia, Jouy, Eric, Chisnall, Thomas, Davies, Alistair R., Schwarz, Stefan, Feßler, Andrea T., Ahrens, Tanja, Jahnen, Johanna, Alter, Thomas, Fleischmann, Susanne, Hammerl, Jens Andre, Jäckel, Claudia, Gieseker, Charles, Crosby, Tina C., Kittel, Elliott C., Miller, Ron A., Alexander, Trevor, Carranza, Kayleigh, Burbick, Claire B., Ching, Biyun, Heng Soh, Jun, Chng, You Rong, Wong, Wai Kwan, Fernandez, Charlene J., Chang, Siow Foong, Verner-Jeffreys, David, Powell, Andy
Formato: Journal Article
Lenguaje:Inglés
Publicado: Inter-Research Science Publisher 2024
Materias:
Acceso en línea:https://hdl.handle.net/10568/170059
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author Smith, Peter
Joseph, Andrew
Baker-Austin, Craig
Kang, Nisha
Baron, Sandrine
Le Devendec, Laëtitia
Jouy, Eric
Chisnall, Thomas
Davies, Alistair R.
Schwarz, Stefan
Feßler, Andrea T.
Ahrens, Tanja
Jahnen, Johanna
Alter, Thomas
Fleischmann, Susanne
Hammerl, Jens Andre
Jäckel, Claudia
Gieseker, Charles
Crosby, Tina C.
Kittel, Elliott C.
Miller, Ron A.
Alexander, Trevor
Carranza, Kayleigh
Burbick, Claire B.
Ching, Biyun
Heng Soh, Jun
Chng, You Rong
Wong, Wai Kwan
Fernandez, Charlene J.
Chang, Siow Foong
Verner-Jeffreys, David
Powell, Andy
author_browse Ahrens, Tanja
Alexander, Trevor
Alter, Thomas
Baker-Austin, Craig
Baron, Sandrine
Burbick, Claire B.
Carranza, Kayleigh
Chang, Siow Foong
Ching, Biyun
Chisnall, Thomas
Chng, You Rong
Crosby, Tina C.
Davies, Alistair R.
Fernandez, Charlene J.
Feßler, Andrea T.
Fleischmann, Susanne
Gieseker, Charles
Hammerl, Jens Andre
Heng Soh, Jun
Jahnen, Johanna
Joseph, Andrew
Jouy, Eric
Jäckel, Claudia
Kang, Nisha
Kittel, Elliott C.
Le Devendec, Laëtitia
Miller, Ron A.
Powell, Andy
Schwarz, Stefan
Smith, Peter
Verner-Jeffreys, David
Wong, Wai Kwan
author_facet Smith, Peter
Joseph, Andrew
Baker-Austin, Craig
Kang, Nisha
Baron, Sandrine
Le Devendec, Laëtitia
Jouy, Eric
Chisnall, Thomas
Davies, Alistair R.
Schwarz, Stefan
Feßler, Andrea T.
Ahrens, Tanja
Jahnen, Johanna
Alter, Thomas
Fleischmann, Susanne
Hammerl, Jens Andre
Jäckel, Claudia
Gieseker, Charles
Crosby, Tina C.
Kittel, Elliott C.
Miller, Ron A.
Alexander, Trevor
Carranza, Kayleigh
Burbick, Claire B.
Ching, Biyun
Heng Soh, Jun
Chng, You Rong
Wong, Wai Kwan
Fernandez, Charlene J.
Chang, Siow Foong
Verner-Jeffreys, David
Powell, Andy
author_sort Smith, Peter
collection Repository of Agricultural Research Outputs (CGSpace)
description This work was performed to generate the data needed to set epidemiological cut-off values for minimal inhibitory concentrations (MICs) of 10 antimicrobial agents against Vibrio parahaemolyticus determined using standardised broth microdilution protocols. Eight laboratories performed broth microdilution tests with incubation at 35°C for 16 to 20 h, and 7 also performed tests on the same isolates with incubation at 28°C for 24 to 28 h. Data were analysed by the ECOFFinder and normalised resistance interpretation algorithms. The cut-off values calculated for ceftazidime, florfenicol and trimethoprim/sulfamethoxazole, 1, 1 and 0.25/4.75 µg ml-1, respectively, were the same when calculated from data obtained at both temperatures. The cut-off values calculated from data obtained at 35°C and from data obtained at 28°C were 0.25 and 0.5 µg ml-1 for enrofloxacin, 2 and 4 µg ml-1 for gentamicin, 0.5 and 1 µg ml-1 for oxolinic acid and 2 and 1 µg ml-1 for oxytetracycline, respectively. The influence of incubation temperature on MIC values was investigated by comparing MICs obtained at 35 and 28°C for a specific antimicrobial agent with a particular isolate by an individual laboratory. Results showed that 56% of 1473 of these paired MIC values were identical, while 38% differed from one another by not more than 1 dilution step. The data generated in this work will be submitted to the Clinical and Laboratory Standards Institute for consideration in their setting of internationally agreed epidemiological cut-off values for V. parahaemolyticus that are essential for interpreting antimicrobial susceptibility testing data of this species.
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spelling CGSpace1700592025-12-08T09:54:28Z Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C Smith, Peter Joseph, Andrew Baker-Austin, Craig Kang, Nisha Baron, Sandrine Le Devendec, Laëtitia Jouy, Eric Chisnall, Thomas Davies, Alistair R. Schwarz, Stefan Feßler, Andrea T. Ahrens, Tanja Jahnen, Johanna Alter, Thomas Fleischmann, Susanne Hammerl, Jens Andre Jäckel, Claudia Gieseker, Charles Crosby, Tina C. Kittel, Elliott C. Miller, Ron A. Alexander, Trevor Carranza, Kayleigh Burbick, Claire B. Ching, Biyun Heng Soh, Jun Chng, You Rong Wong, Wai Kwan Fernandez, Charlene J. Chang, Siow Foong Verner-Jeffreys, David Powell, Andy vibrio parahaemolyticus antimicrobial mic epidemiological cut-off values minimal inhibitory concentration incubation temperature cowt This work was performed to generate the data needed to set epidemiological cut-off values for minimal inhibitory concentrations (MICs) of 10 antimicrobial agents against Vibrio parahaemolyticus determined using standardised broth microdilution protocols. Eight laboratories performed broth microdilution tests with incubation at 35°C for 16 to 20 h, and 7 also performed tests on the same isolates with incubation at 28°C for 24 to 28 h. Data were analysed by the ECOFFinder and normalised resistance interpretation algorithms. The cut-off values calculated for ceftazidime, florfenicol and trimethoprim/sulfamethoxazole, 1, 1 and 0.25/4.75 µg ml-1, respectively, were the same when calculated from data obtained at both temperatures. The cut-off values calculated from data obtained at 35°C and from data obtained at 28°C were 0.25 and 0.5 µg ml-1 for enrofloxacin, 2 and 4 µg ml-1 for gentamicin, 0.5 and 1 µg ml-1 for oxolinic acid and 2 and 1 µg ml-1 for oxytetracycline, respectively. The influence of incubation temperature on MIC values was investigated by comparing MICs obtained at 35 and 28°C for a specific antimicrobial agent with a particular isolate by an individual laboratory. Results showed that 56% of 1473 of these paired MIC values were identical, while 38% differed from one another by not more than 1 dilution step. The data generated in this work will be submitted to the Clinical and Laboratory Standards Institute for consideration in their setting of internationally agreed epidemiological cut-off values for V. parahaemolyticus that are essential for interpreting antimicrobial susceptibility testing data of this species. 2024-12-12 2025-01-27T08:42:08Z 2025-01-27T08:42:08Z Journal Article https://hdl.handle.net/10568/170059 en Open Access application/pdf Inter-Research Science Publisher Peter Smith, Andrew Joseph, Craig Baker-Austin, Nisha Kang, Sandrine Baron, Laëtitia Le Devendec, Eric Jouy, Thomas Chisnall, Alistair R. Davies, Stefan Schwarz, Andrea T. Feßler, Tanja Ahrens, Johanna Jahnen, Thomas Alter, Susanne Fleischmann, Jens Andre Hammerl, Claudia Jäckel, Charles Gieseker, Tina C. Crosby, Elliott C. Kittel, Ron A. Miller, Trevor Alexander, Kayleigh Carranza, Claire B. Burbick, Biyun Ching, Jun Heng Soh, You Rong Chng, Wai Kwan Wong, Charlene J. Fernandez, Siow Foong Chang, David Verner-Jeffreys, Andy Powell. (12/12/2024). Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C. Diseases of Aquatic Organisms, 160.
spellingShingle vibrio parahaemolyticus
antimicrobial
mic
epidemiological cut-off values
minimal inhibitory concentration
incubation temperature
cowt
Smith, Peter
Joseph, Andrew
Baker-Austin, Craig
Kang, Nisha
Baron, Sandrine
Le Devendec, Laëtitia
Jouy, Eric
Chisnall, Thomas
Davies, Alistair R.
Schwarz, Stefan
Feßler, Andrea T.
Ahrens, Tanja
Jahnen, Johanna
Alter, Thomas
Fleischmann, Susanne
Hammerl, Jens Andre
Jäckel, Claudia
Gieseker, Charles
Crosby, Tina C.
Kittel, Elliott C.
Miller, Ron A.
Alexander, Trevor
Carranza, Kayleigh
Burbick, Claire B.
Ching, Biyun
Heng Soh, Jun
Chng, You Rong
Wong, Wai Kwan
Fernandez, Charlene J.
Chang, Siow Foong
Verner-Jeffreys, David
Powell, Andy
Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C
title Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C
title_full Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C
title_fullStr Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C
title_full_unstemmed Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C
title_short Epidemiological cut-off values for Vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C
title_sort epidemiological cut off values for vibrio parahaemo lyticus calculated from minimal inhibitory concentration data generated at 35 and 28°c
topic vibrio parahaemolyticus
antimicrobial
mic
epidemiological cut-off values
minimal inhibitory concentration
incubation temperature
cowt
url https://hdl.handle.net/10568/170059
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