Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa
Crimean Congo hemorrhagic fever (CCHF) is a re-emerging tick-borne zoonosis that is caused by CCHF virus (CCHFV). The geographical distribution of the disease and factors that influence its occurrence are poorly known. We analysed historical records on its outbreaks in various countries across the s...
| Autores principales: | , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
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Nature Research
2025
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| Acceso en línea: | https://hdl.handle.net/10568/169454 |
| _version_ | 1855537501745184768 |
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| author | Ilboudo, Abdoul K. Oloo, Stephen O. Sircely, Jason Nijhof, A.M. Bett, Bernard K. |
| author_browse | Bett, Bernard K. Ilboudo, Abdoul K. Nijhof, A.M. Oloo, Stephen O. Sircely, Jason |
| author_facet | Ilboudo, Abdoul K. Oloo, Stephen O. Sircely, Jason Nijhof, A.M. Bett, Bernard K. |
| author_sort | Ilboudo, Abdoul K. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Crimean Congo hemorrhagic fever (CCHF) is a re-emerging tick-borne zoonosis that is caused by CCHF virus (CCHFV). The geographical distribution of the disease and factors that influence its occurrence are poorly known. We analysed historical records on its outbreaks in various countries across the sub-Saharan Africa (SSA) to identify hotspots and determine socioecological and demographic factors associated with these outbreaks. We used data from historical outbreaks that were reported between 1981 and 2022 in various countries in SSA. To develop a common framework for merging the outbreak data and potential explanatory variables, we generated a common shapefile that combined Level 2 administrative units in all the countries. Several climatic, environmental, socioecological data were obtained from on-line GIS databases and extracted using the shapefile. The data were analysed using an approximate Bayesian hierarchical model using the R-INLA package. The outcome was a Boolean variable which indicated whether an administrative unit in the shapefile was affected in a given year or not. A neighborhood structure was also generated and used to account for spatial autocorrelation in the analysis. The final model that was obtained from the analysis was used to build a CCHF risk map. A total of 54 CCHF outbreaks were compiled across 414 districts in nine SSA countries. Factors that were positively associated with CCHF outbreaks included human population density, land area under grassland, bare soil cover and shrub cover. Conversely, high precipitation during wet months, elevated mean temperature and slope had negative effects. The risk map generated shows that CCHF occurrence risk is higher in arid and semi-arid land (ASAL) of West Africa, the Sahelian region, Central Africa, and the Eastern and Southern Africa region. The analysis identified ecological and demographic factors that are associated with CCHF outbreaks in SSA. This finding suggests the need to improve surveillance for the disease especially in the grasslands where the human population is increasing. |
| format | Journal Article |
| id | CGSpace169454 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Nature Research |
| publisherStr | Nature Research |
| record_format | dspace |
| spelling | CGSpace1694542025-10-26T12:51:12Z Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa Ilboudo, Abdoul K. Oloo, Stephen O. Sircely, Jason Nijhof, A.M. Bett, Bernard K. crimean-congo haemorrhagic fever epidemiology zoonoses Crimean Congo hemorrhagic fever (CCHF) is a re-emerging tick-borne zoonosis that is caused by CCHF virus (CCHFV). The geographical distribution of the disease and factors that influence its occurrence are poorly known. We analysed historical records on its outbreaks in various countries across the sub-Saharan Africa (SSA) to identify hotspots and determine socioecological and demographic factors associated with these outbreaks. We used data from historical outbreaks that were reported between 1981 and 2022 in various countries in SSA. To develop a common framework for merging the outbreak data and potential explanatory variables, we generated a common shapefile that combined Level 2 administrative units in all the countries. Several climatic, environmental, socioecological data were obtained from on-line GIS databases and extracted using the shapefile. The data were analysed using an approximate Bayesian hierarchical model using the R-INLA package. The outcome was a Boolean variable which indicated whether an administrative unit in the shapefile was affected in a given year or not. A neighborhood structure was also generated and used to account for spatial autocorrelation in the analysis. The final model that was obtained from the analysis was used to build a CCHF risk map. A total of 54 CCHF outbreaks were compiled across 414 districts in nine SSA countries. Factors that were positively associated with CCHF outbreaks included human population density, land area under grassland, bare soil cover and shrub cover. Conversely, high precipitation during wet months, elevated mean temperature and slope had negative effects. The risk map generated shows that CCHF occurrence risk is higher in arid and semi-arid land (ASAL) of West Africa, the Sahelian region, Central Africa, and the Eastern and Southern Africa region. The analysis identified ecological and demographic factors that are associated with CCHF outbreaks in SSA. This finding suggests the need to improve surveillance for the disease especially in the grasslands where the human population is increasing. 2025-01-17 2025-01-20T11:18:54Z 2025-01-20T11:18:54Z Journal Article https://hdl.handle.net/10568/169454 en Open Access Nature Research Ilboudo, A.K., Oloo, S.O., Sircely, J., Nijhof, A.M. and Bett, B. 2025. Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa. Scientific Reports 15: 2292. |
| spellingShingle | crimean-congo haemorrhagic fever epidemiology zoonoses Ilboudo, Abdoul K. Oloo, Stephen O. Sircely, Jason Nijhof, A.M. Bett, Bernard K. Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa |
| title | Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa |
| title_full | Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa |
| title_fullStr | Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa |
| title_full_unstemmed | Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa |
| title_short | Spatial analysis and risk mapping of Crimean-Congo hemorrhagic fever (CCHF) in sub-Saharan Africa |
| title_sort | spatial analysis and risk mapping of crimean congo hemorrhagic fever cchf in sub saharan africa |
| topic | crimean-congo haemorrhagic fever epidemiology zoonoses |
| url | https://hdl.handle.net/10568/169454 |
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