The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants

The ‘Mycoplasma mycoides cluster’ comprises the ruminant pathogens Mycoplasma mycoides subsp. mycoides the causative agent of contagious bovine pleuropneumonia (CBPP), Mycoplasma capricolum subsp. capripneumoniae the agent of contagious caprine pleuropneumonia (CCPP), Mycoplasma capricolum subsp. ca...

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Autores principales: Fischer, A., Shapiro, Barry I., Muriuki, C., Heller, M., Schnee, C., Bongcam-Rudloff, E., Frey, J., Jores, Joerg
Formato: Journal Article
Lenguaje:Inglés
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://hdl.handle.net/10568/16907
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author Fischer, A.
Shapiro, Barry I.
Muriuki, C.
Heller, M.
Schnee, C.
Bongcam-Rudloff, E.
Frey, J.
Jores, Joerg
author_browse Bongcam-Rudloff, E.
Fischer, A.
Frey, J.
Heller, M.
Jores, Joerg
Muriuki, C.
Schnee, C.
Shapiro, Barry I.
author_facet Fischer, A.
Shapiro, Barry I.
Muriuki, C.
Heller, M.
Schnee, C.
Bongcam-Rudloff, E.
Frey, J.
Jores, Joerg
author_sort Fischer, A.
collection Repository of Agricultural Research Outputs (CGSpace)
description The ‘Mycoplasma mycoides cluster’ comprises the ruminant pathogens Mycoplasma mycoides subsp. mycoides the causative agent of contagious bovine pleuropneumonia (CBPP), Mycoplasma capricolum subsp. capripneumoniae the agent of contagious caprine pleuropneumonia (CCPP), Mycoplasma capricolum subsp. capricolum, Mycoplasma leachii and Mycoplasma mycoides subsp. capri. CBPP and CCPP are major livestock diseases and impact the agricultural sector especially in developing countries through reduced food-supply and international trade restrictions. In addition, these diseases are a threat to disease-free countries. We used a multilocus sequence typing (MLST) approach to gain insights into the demographic history of and phylogenetic relationships among the members of the ‘M. mycoides cluster’. We collected partial sequences from seven housekeeping genes representing a total of 3,816 base pairs from 118 strains within this cluster, and five strains isolated from wild Caprinae. Strikingly, the origin of the ‘M. mycoides cluster’ dates to about 10,000 years ago, suggesting that the establishment and spread of the cluster coincided with livestock domestication. In addition, we show that hybridization and recombination may be important factors in the evolutionary history of the cluster.
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spelling CGSpace169072024-01-09T09:50:01Z The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants Fischer, A. Shapiro, Barry I. Muriuki, C. Heller, M. Schnee, C. Bongcam-Rudloff, E. Frey, J. Jores, Joerg contagious caprine pleuropneumonia cattle goats The ‘Mycoplasma mycoides cluster’ comprises the ruminant pathogens Mycoplasma mycoides subsp. mycoides the causative agent of contagious bovine pleuropneumonia (CBPP), Mycoplasma capricolum subsp. capripneumoniae the agent of contagious caprine pleuropneumonia (CCPP), Mycoplasma capricolum subsp. capricolum, Mycoplasma leachii and Mycoplasma mycoides subsp. capri. CBPP and CCPP are major livestock diseases and impact the agricultural sector especially in developing countries through reduced food-supply and international trade restrictions. In addition, these diseases are a threat to disease-free countries. We used a multilocus sequence typing (MLST) approach to gain insights into the demographic history of and phylogenetic relationships among the members of the ‘M. mycoides cluster’. We collected partial sequences from seven housekeeping genes representing a total of 3,816 base pairs from 118 strains within this cluster, and five strains isolated from wild Caprinae. Strikingly, the origin of the ‘M. mycoides cluster’ dates to about 10,000 years ago, suggesting that the establishment and spread of the cluster coincided with livestock domestication. In addition, we show that hybridization and recombination may be important factors in the evolutionary history of the cluster. 2012-04-27 2012-05-02T17:02:02Z 2012-05-02T17:02:02Z Journal Article https://hdl.handle.net/10568/16907 en Open Access Public Library of Science Fischer, A., Shapiro, B., Muriuki, C., Heller, M., Schnee, C., Bongcam-Rudloff, E., Frey, J. and J. Jores. 2012. The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants. PLoS ONE 7(4): e36150.
spellingShingle contagious caprine pleuropneumonia
cattle
goats
Fischer, A.
Shapiro, Barry I.
Muriuki, C.
Heller, M.
Schnee, C.
Bongcam-Rudloff, E.
Frey, J.
Jores, Joerg
The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants
title The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants
title_full The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants
title_fullStr The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants
title_full_unstemmed The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants
title_short The origin of the Mycoplasma mycoides cluster coincides with domestication of ruminants
title_sort origin of the mycoplasma mycoides cluster coincides with domestication of ruminants
topic contagious caprine pleuropneumonia
cattle
goats
url https://hdl.handle.net/10568/16907
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